Evidence map›Paper›PMID 40971849›Full record

ArticlePloS one2025

Performance of large language models ChatGPT and Gemini in child and adolescent psychiatry knowledge assessment.

Johanna Charlotte Neubauer, Anna Kaiser, Leon Lettermann, Tobias Volkert, Alexander Häge

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Article in PloS one, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Johanna Charlotte NeubauerCentral Institute of Mental Health, Mannheim, Baden-Württemberg, Germany.ORCID 0000-0002-0234-6529
Anna KaiserCentral Institute of Mental Health, Mannheim, Baden-Württemberg, Germany.
Leon LettermannBioquant-Center & Institute for Theoretical Physics, Heidelberg University, Heidelberg, Baden-Württemberg, Germany.ORCID 0009-0004-7989-9123
Tobias VolkertIndependent Researcher, Heidelberg, Baden-Württemberg, Germany.
Alexander HägeCentral Institute of Mental Health, Mannheim, Baden-Württemberg, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis study evaluates the performance of four large language models-ChatGPT 4o, ChatGPT o1-mini, Gemini 2.0 Flash, and Gemini 1.5 Flash-in answering multiple-choice questions in child and adolescent psychiatry to assess their level of factual knowledge in the field.

methodsA total of 150 standardized multiple-choice questions from a specialty board review study guide were selected, ensuring a representative distribution across different topics. Each question had five possible answers, with only one correct option. To account for the stochastic nature of large language models, each question was asked 10 times with randomized answer orders to minimize known biases. Accuracy for each question was assessed as the percentage of correct answers across 10 requests. We calculated the mean accuracy for each model and performed statistical comparisons using paired t-tests to evaluate differences between Gemini 2.0 Flash and Gemini 1.5 Flash, as well as between Gemini 2.0 Flash and both ChatGPT 4o and ChatGPT o1-mini. As a post-hoc exploration, we identified questions with an accuracy below 10% across all models to highlight areas of particularly low performance.

resultsThe accuracy of the tested models ranged from 68.3% to 78.9%. Both ChatGPT and Gemini demonstrated generally solid performance in the assessment of in child and adolescent psychiatry knowledge, with variations between models and topics. The superior performance of Gemini 2.0 Flash compared with its predecessor, Gemini 1.5 Flash, may reflect advancements in artificial intelligence capabilities. Certain topics, such as psychopharmacology, posed greater challenges compared to disorders with well-defined diagnostic criteria, such as schizophrenia or eating disorders.

conclusionWhile the results indicate that language models can support knowledge acquisition in child and adolescent psychiatry, limitations remain. Variability in accuracy across different topics, potential biases, and risks of misinterpretation must be carefully considered before implementing these models in clinical decision-making.

Indexed as

Adolescent PsychiatryChild PsychiatryEducational MeasurementLanguageAdolescentChildGenerative Artificial IntelligenceHumansLarge Language ModelsSurveys and Questionnaires

Identifiers

PMID40971849
PMCPMC12449005

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.