ArticlePloS one2025
Performance of large language models ChatGPT and Gemini in child and adolescent psychiatry knowledge assessment.
Article in PloS one, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- A Comparative Evaluation of Three Large Language Models for Parent-Centered Questions About Anorexia Nervosa.The International journal of eating disorders · 2026Article
- AI-based decision support in pediatric dentistry: a comparative study of ChatGPT-5 and gemini advanced.BMC oral health · 2026Article
- Evaluating the accuracy and communication quality of large language models in Ewing sarcoma: a comparative analysis of ChatGPT, Claude, Gemini, DeepSeek, and Grok.Frontiers in pediatrics · 2026Article
- Assessing large language model responses to pediatric depression FAQs: a cross-sectional study on readability, accuracy, and sentiment.Frontiers in psychiatry · 2026Article
- From digital assistants to clinical partners: revolutionizing pediatric urology through large language model-powered decision support and patient education.World journal of urology · 2025Article
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5 authors.
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Abstract
objectiveThis study evaluates the performance of four large language models-ChatGPT 4o, ChatGPT o1-mini, Gemini 2.0 Flash, and Gemini 1.5 Flash-in answering multiple-choice questions in child and adolescent psychiatry to assess their level of factual knowledge in the field.
methodsA total of 150 standardized multiple-choice questions from a specialty board review study guide were selected, ensuring a representative distribution across different topics. Each question had five possible answers, with only one correct option. To account for the stochastic nature of large language models, each question was asked 10 times with randomized answer orders to minimize known biases. Accuracy for each question was assessed as the percentage of correct answers across 10 requests. We calculated the mean accuracy for each model and performed statistical comparisons using paired t-tests to evaluate differences between Gemini 2.0 Flash and Gemini 1.5 Flash, as well as between Gemini 2.0 Flash and both ChatGPT 4o and ChatGPT o1-mini. As a post-hoc exploration, we identified questions with an accuracy below 10% across all models to highlight areas of particularly low performance.
resultsThe accuracy of the tested models ranged from 68.3% to 78.9%. Both ChatGPT and Gemini demonstrated generally solid performance in the assessment of in child and adolescent psychiatry knowledge, with variations between models and topics. The superior performance of Gemini 2.0 Flash compared with its predecessor, Gemini 1.5 Flash, may reflect advancements in artificial intelligence capabilities. Certain topics, such as psychopharmacology, posed greater challenges compared to disorders with well-defined diagnostic criteria, such as schizophrenia or eating disorders.
conclusionWhile the results indicate that language models can support knowledge acquisition in child and adolescent psychiatry, limitations remain. Variability in accuracy across different topics, potential biases, and risks of misinterpretation must be carefully considered before implementing these models in clinical decision-making.
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