Evidence map›Paper›PMID 40971549›Full record

ArticleMedical care2025

Loneliness and Risk of 30-Day Hospital Readmission After Acute Myocardial Infarction.

Cheyenne Acker, Orysya Soroka, Madeline R Sterling, Parag Goyal, Monika M Safford, Laura C Pinheiro

Abstract read
In one paragraph

Article in Medical care, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Cheyenne AckerDepartment of Medicine, Division of General Internal Medicine, Weill Cornell Medicine, New York, NY.ORCID 0000-0003-1601-0636
Orysya Soroka
Madeline R Sterling
Parag Goyal
Monika M Safford
Laura C Pinheiro

Funding

VCID and Stroke in a Bi-racial National CohortU01NS041588 · NINDS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI CUSHMAN, MARY, HOWARD, GEORGE · 2002 to 2022
$96.0M
REasons for Geographic And Racial Differences in Stroke-Myocardial Infarction-4 (REGARDS-MI-4)R01HL165452 · NHLBI · WEILL MEDICAL COLL OF CORNELL UNIV · PI LEVITAN, EMILY B, SAFFORD, MONIKA M · 2022 to 2025
$8.3M
Structural Racism and Cardiovascular Outcomes Among Cancer SurvivorsR37CA288492 · NCI · WEILL MEDICAL COLL OF CORNELL UNIV · PI Laura C Pinheiro · 2024 to 2026
$1.9M
NCI NIH HHS R37 CA288492NHLBI NIH HHS R01 HL165452NINDS NIH HHS U01 NS041588
6 · The paper itself

Abstract

backgroundPoor social health is linked to incident cardiovascular disease, but less is known about how loneliness affects health care utilization after an acute myocardial infarction (AMI).

objectiveDetermine the association between loneliness and 30-day emergency department (ED) visit or readmission after AMI hospitalization. RESEARCH

designThe REasons for Geographic and Racial Differences in Stroke (REGARDS) study is a national prospective cohort of 30,239 U.S. adults aged 45 years or older. MEASURES: We examined the association between loneliness and 30-day post-AMI ED visit or readmission. SUBJECTS: Seven hundred forty-nine Medicare fee-for-service beneficiaries in REGARDS were discharged alive after an adjudicated AMI.

resultsThe mean age was 77 years. Twenty-eight percent self-identified as non-Hispanic Black and 39% as women. Twenty percent reported loneliness. Twenty-nine percent had a 30-day ED visit or readmission. Lonely individuals had 61% increased risk of 30-day ED visit or readmission (RR: 1.61; 95% CI: 1.27-2.04; P <0.001), which remained significant after adjustment for sociodemographic and clinical factors (aRR: 1.48; 95% CI: 1.12-1.95; P =0.006). Stratified analyses demonstrated significant association for those aged 65-74 (aRR 2.48; 95% CI, 1.57-3.91; P <0.001), White adults (aRR: 1.86; 95% CI: 1.35-2.58; P <0.001), and men (aRR: 2.19; 95% CI: 1.59-3.01; P <0.001) but not for those 75+ (aRR: 0.94; 95% CI: 0.63-1.40; P =0.75), Black adults (aRR: 0.89; 95% CI: 0.53-1.49; P =0.660), or women (aRR: 0.81; 95% CI: 0.51-1.30; P =0.380).

conclusionsLoneliness, even measured years before AMI, was associated with an increased risk of 30-day ED visit or readmission, specifically for those aged 65-74, White participants, and men. These findings may inform discharge strategies to reduce readmissions.

Indexed as

Emergency Service, HospitalLonelinessMyocardial InfarctionPatient ReadmissionAgedAged, 80 and overFemaleHumansMaleMedicareMiddle AgedProspective StudiesRisk FactorsSex FactorsSocioeconomic FactorsUnited StatesMedicaremyocardial infarctionreadmissionssocial support

Identifiers

PMID40971549
PMCPMC13054470

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.