Evidence map›Paper›PMID 40971079›Full record

ArticleActa neurochirurgica2025

How I do it: > 8 Carmustine wafer implantation during supra-marginal resection of a glioblastoma, IDH-wildtype.

Alexandre Roux, Angela Elia, Marc Zanello, Johan Pallud

Abstract read
In one paragraph

Article in Acta neurochirurgica, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Alexandre RouxService de Neurochirurgie, GHU-Paris Psychiatrie Et Neurosciences, Site Sainte Anne, Paris, F-75014, France. alexandre.roux@neurochirurgie.fr.
Angela EliaService de Neurochirurgie, GHU-Paris Psychiatrie Et Neurosciences, Site Sainte Anne, Paris, F-75014, France.
Marc ZanelloService de Neurochirurgie, GHU-Paris Psychiatrie Et Neurosciences, Site Sainte Anne, Paris, F-75014, France.
Johan PalludService de Neurochirurgie, GHU-Paris Psychiatrie Et Neurosciences, Site Sainte Anne, Paris, F-75014, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe maximal safe resection of glioblastoma, IDH-wildtype often creates a large resection cavity that can accommodate more than eight Carmustine implants.

methodWe detail the implantation technique of 13 Carmustine wafers within the surgical bed after a right hippocampal formation-sparing anterior temporal lobectomy allowing for the supra-marginal resection of a glioblastoma IDH-wildtype in an adult patient.

conclusionCarmustine wafer implantation is a safe and efficient technique following surgical resection of a glioblastoma, IDH-wildtype. Sequential technical steps are required to improve the safety and the efficacy of Carmustine wafer implantation. More than eight Carmustine wafers could be implanted in large surgical cavities with survival benefits for the patients.

Indexed as

Antineoplastic Agents, AlkylatingBrain NeoplasmsCarmustineGlioblastomaNeurosurgical ProceduresAdultDrug ImplantsHumansIsocitrate DehydrogenaseAntineoplastic Agents, AlkylatingCarmustineDrug ImplantsIsocitrate DehydrogenaseCarmustine wafer implantationGlioblastomaIDH-wildtypeNeurosurgery

Identifiers

PMID40971079
PMCPMC12449338

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.