Evidence map›Paper›PMID 40970972›Full record

ArticleTAG. Theoretical and applied genetics. Theoretische und angewandte Genetik2025

GmCDC7 is involved in coordinating seed size and quality in soybean.

Ce Yang, Bingbing Li, Hongqiang Yu, Yan Wang, Zhenghong An, Manying Chen, Chaoying He

Abstract read
PubMed Publisher
In one paragraph

Article in TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ce YangState Key Laboratory of Plant Diversity and Specialty Crops/Laboratory of Systematic and Evolutionary Botany, Institute of Botany, Chinese Academy of Sciences, Beijing, 100093, China.
Bingbing LiState Key Laboratory of Plant Diversity and Specialty Crops/Laboratory of Systematic and Evolutionary Botany, Institute of Botany, Chinese Academy of Sciences, Beijing, 100093, China.
Hongqiang YuState Key Laboratory of Plant Diversity and Specialty Crops/Laboratory of Systematic and Evolutionary Botany, Institute of Botany, Chinese Academy of Sciences, Beijing, 100093, China.
Yan WangState Key Laboratory of Plant Diversity and Specialty Crops/Laboratory of Systematic and Evolutionary Botany, Institute of Botany, Chinese Academy of Sciences, Beijing, 100093, China.
Zhenghong AnState Key Laboratory of Plant Diversity and Specialty Crops/Laboratory of Systematic and Evolutionary Botany, Institute of Botany, Chinese Academy of Sciences, Beijing, 100093, China.
Manying ChenState Key Laboratory of Plant Diversity and Specialty Crops/Laboratory of Systematic and Evolutionary Botany, Institute of Botany, Chinese Academy of Sciences, Beijing, 100093, China.
Chaoying HeState Key Laboratory of Plant Diversity and Specialty Crops/Laboratory of Systematic and Evolutionary Botany, Institute of Botany, Chinese Academy of Sciences, Beijing, 100093, China. chaoying@ibcas.ac.cn.ORCID http://orcid.org/0000-0002-2550-0170

Funding

Biological Breeding-National Science and Technology Major Project 2023ZD0406802Biological Breeding-National Science and Technology Major Project 2023ZD0406904Chinese Academy of Sciences XDA08010105National Natural Science Foundation of China 31525003National Natural Science Foundation of China 31930007
6 · The paper itself

Abstract

key messageWe revealed essential roles of GmCDC7 in modulating seed size/weight and seed protein/oil content in soybean, presenting potential new targets for improving yield and quality of soybean and other crops. Seed size/weight is a critical factor determining crop yield; however, a limited number of genes regulating this trait have been characterized in soybean. In this study, we identified a Glycine max CELL DIVISION CYCLE 7 (GmCDC7) and revealed its essential roles in seed development. The putative GmCDC7 was highly conserved in both sequences and structure across various species. GmCDC7 transcripts were detectable in multiple tissues, with peak expression occurring during early seed development, while the GmCDC7 proteins were predominantly localized within the nucleus. CRISPR/Cas9-mediated knockout of GmCDC7 led to a significant increase in seed size and 100-seed weight, while overexpression of this gene resulted in a reduction in both seed size and weight. Further cytological analysis demonstrated that GmCDC7 promoted cell expansion and inhibited cell proliferation in seeds. Notably, the gene-edited gmcdc7 mutants showed a substantial increase in protein content alongside a reduction in oil content in seeds. Correspondingly, transcriptomic analyses revealed that GmCDC7 may significantly influence multifaceted regulatory pathways related to cell cycle-related activities, storage protein accumulation, and lipid transport and metabolism during seed development. These findings suggest that GmCDC7 plays pivotal roles in modulating seed size/weight and quality, offering new gene resources and insights into biotechnological strategies for soybean breeding.

Indexed as

Cell Cycle ProteinsGlycine maxPlant ProteinsSeedsCRISPR-Cas SystemsGene Expression Regulation, PlantPhenotypePlants, Genetically ModifiedCell Cycle ProteinsPlant Proteins

Identifiers

PMID40970972

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.