Evidence map›Paper›PMID 40970715›Full record

ArticleJournal of clinical microbiology2025

An extraction-free and one-pot two-temperature CRISPR/Cas12b system for visual detection of Group B

Chengman Zhao, Ge Li, Chen Shen, Yanjun Xie, Yun Chen, Xiaobo Ying, Yan Chen, Chuanling Zhang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of clinical microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Rapid detection ofFrontiers in microbiology · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Chengman Zhao *Department of Internal Medicine, Affiliated Xiaoshan Hospital, Hangzhou Normal University, Hangzhou, China.
Ge Li *Department of Internal Medicine, Hangzhou Mingzhou Brain Rehabilitation Hospital, Hangzhou, China.
Chen Shen *Department of Clinical Laboratory, Affiliated Xiaoshan Hospital, Hangzhou Normal University, Hangzhou, China.
Yanjun XieDepartment of Clinical Laboratory, Affiliated Xiaoshan Hospital, Hangzhou Normal University, Hangzhou, China.
Yun ChenDepartment of Obstetrics and Gynecology, Affiliated Xiaoshan Hospital, Hangzhou Normal University, Hangzhou, China.
Xiaobo YingDepartment of Internal Medicine, Affiliated Xiaoshan Hospital, Hangzhou Normal University, Hangzhou, China.
Yan ChenTranslational Medicine Laboratory, Affiliated Xiaoshan Hospital, Hangzhou Normal University, Hangzhou, China.
Chuanling ZhangTranslational Medicine Laboratory, Affiliated Xiaoshan Hospital, Hangzhou Normal University, Hangzhou, China.ORCID 0009-0007-7834-3053

Funding

Medical and Health Research Project of Zhejiang Province 2024KY1444Zhejiang Provincial Natural Science Foundation of China LTGC23H200004
6 · The paper itself

Abstract

Group B IMPORTANCE: This study presents a rapid, convenient, and highly accurate method for Group B

Indexed as

CRISPR-Cas SystemsMolecular Diagnostic TechniquesNucleic Acid Amplification TechniquesStreptococcal InfectionsStreptococcus agalactiaeFemaleHumansRecombinasesSensitivity and SpecificityTemperatureVaginaRecombinasesCRISPR/Cas12bextraction-freeGroup B StreptococcusLAMPone-pot two-temperatureRPA

Identifiers

PMID40970715
PMCPMC12506078

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.