Evidence map›Paper›PMID 40970708›Full record

ArticleJournal of bacteriology2025

Mechanisms of 10-hydroxyoctadecanoic acid resistance in

Cydney N Johnson, Matthew W Frank, Chrispin Chaguza, Brendan T Morrow, Qidong Jia, Christopher D Radka, Jason W Rosch

Abstract read
In one paragraph

Article in Journal of bacteriology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Cydney N JohnsonDepartment of Host-Microbe Interactions, St Jude Children's Research Hospital, Memphis, Tennessee, USA.ORCID 0000-0002-3190-4972
Matthew W FrankDepartment of Host-Microbe Interactions, St Jude Children's Research Hospital, Memphis, Tennessee, USA.
Chrispin ChaguzaDepartment of Host-Microbe Interactions, St Jude Children's Research Hospital, Memphis, Tennessee, USA.
Brendan T MorrowDepartment of Host-Microbe Interactions, St Jude Children's Research Hospital, Memphis, Tennessee, USA.
Qidong JiaDepartment of Host-Microbe Interactions, St Jude Children's Research Hospital, Memphis, Tennessee, USA.
Christopher D RadkaDepartment of Microbiology, Immunology, and Molecular Genetics, University of Kentucky, Lexington, Kentucky, USA.ORCID 0000-0002-6037-7710
Jason W RoschDepartment of Host-Microbe Interactions, St Jude Children's Research Hospital, Memphis, Tennessee, USA.ORCID 0000-0002-1798-1760

Funding

Viral Vector Technology (VVTSR)P30CA021765 · NCI · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI Shondra Michelle Miller · 1985 to 2026
$166.9M
Drug resistance enablers and their role in antibiotic treatment failureU19AI158076 · NIAID · BROAD INSTITUTE, INC. · PI VAN OPIJNEN, TIM · 2022 to 2025
$10.0M
Consequences of Direct Viral-Bacterial InteractionsR01AI168214 · NIAID · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI Jason W. Rosch, Stacey L Schultz-Cherry · 2022 to 2026
$2.5M
Training in the Design and Development of Infectious Disease TherapeuticsT32AI106700 · NIAID · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI Richard E. Lee · 2015 to 2026
$2.1M
[18F]fluoromannitol: A novel imaging agent to delineate osteomyelitis in sickle cell diseaseR01AI192221 · NIAID · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI Amanda Marie Green, Kiel Neumann · 2025 to 2026
$1.8M
Targeting Membrane Environments: The Role of Oleate Hydratase (OhyA) in Lipid-Protein Interactions Across Microbial CommunitiesR35GM159612 · NIGMS · UNIVERSITY OF KENTUCKY · PI Christopher David Radka · 2025 to 2026
$824k
Bacterial anti-inflammatory lipid mediatorsR00AI166116 · NIAID · UNIVERSITY OF KENTUCKY · PI RADKA, CHRISTOPHER DAVID · 2023 to 2025
$733k
Contribution of Toll-like receptor signaling in islet transplantationK08AI071038 · NIAID · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI SCHROPPEL, BERND · 2007 to 2010
$618k
Trivalent Live Attenuated Vaccines for Bacterial Acute Otitis MediaR21AI178085 · NIAID · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI ROSCH, JASON W. · 2024 to 2025
$494k
Characterization of TCS11 in Streptococcus pneumoniaeR21AI178084 · NIAID · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI MARGOLIS, ELISA B H, ROSCH, JASON W. · 2024 to 2025
$494k
National Institute of Allergy and Infectious Diseases 1U19AI158076National Institute of Allergy and Infectious Diseases F32-AI286447National Institute of Allergy and Infectious Diseases P30National Institute of Allergy and Infectious Diseases R00-AI166116National Institute of Allergy and Infectious Diseases R01AI168214National Institute of Allergy and Infectious Diseases R01AI192221National Institute of Allergy and Infectious Diseases R01AI71038National Institute of Allergy and Infectious Diseases R21AI178084National Institute of Allergy and Infectious Diseases R21AI178085National Institute of Allergy and Infectious Diseases T32-AI106700NCI NIH HHS P30 CA021765NIAID NIH HHS K08 AI071038NIAID NIH HHS R00 AI166116NIAID NIH HHS R01 AI168214NIAID NIH HHS R01 AI192221NIAID NIH HHS R21 AI178084NIAID NIH HHS R21 AI178085NIAID NIH HHS T32 AI106700NIAID NIH HHS U19 AI158076NIGMS NIH HHS R35 GM159612
6 · The paper itself

Abstract

Profiles of human nasal colonization consistently demonstrate that

Indexed as

Anti-Bacterial AgentsDrug Resistance, BacterialFatty AcidsStreptococcus pneumoniaeBacterial ProteinsHumansNasopharynxStaphylococcus aureusAnti-Bacterial AgentsBacterial ProteinsFatty Acidscell chargefatty acid resistanceglycosyltransferasehydroxy fatty acidlipid profilemembrane compositionphase variationrecombinaseStreptococcus pneumoniae

Identifiers

PMID40970708
PMCPMC12548398

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.