Evidence map›Paper›PMID 40970701›Full record

ArticleApplied and environmental microbiology2025

Diel cycle of lanthanide-dependent methylotrophy by TMED127/Methylaequorales bacteria in oligotrophic surface seawater.

Jennifer B Glass, Leilani N Warters, Abdulaziz M Alajlan

Abstract read
In one paragraph

Article in Applied and environmental microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Jennifer B GlassSchool of Earth and Atmospheric Sciences, Georgia Institute of Technology, Atlanta, Georgia, USA.ORCID 0000-0003-0775-2486
Leilani N WartersSchool of Earth and Atmospheric Sciences, Georgia Institute of Technology, Atlanta, Georgia, USA.
Abdulaziz M AlajlanSchool of Earth and Atmospheric Sciences, Georgia Institute of Technology, Atlanta, Georgia, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Methanol, the simplest alcohol, has long been known to be a key energy and carbon source for soil and plant-associated bacteria and fungi and is increasingly recognized as an important substrate for marine bacteria. Lanthanide-dependent methanol dehydrogenases (encoded by the gene IMPORTANCE: Methanol metabolism is increasingly recognized as an important process in the marine carbon cycle, yet the identity and metabolism of the microorganisms mediating methylotrophy in the open ocean have remained unknown. This study reveals that bacteria in the TMED127 order of Alphaproteobacteria, renamed here as "Methylaequorales," abundantly transcribe the key gene for lanthanide-dependent methylotrophy in oligotrophic surface waters of the world's oceans. TMED127/Methylaequorales likely require methanol as a carbon and energy source and display a diel pattern of transcription of key genes for methylotrophy that peaks in the late afternoon. These findings motivate future studies on the mechanisms of methanol production in surface seawater.

Indexed as

AlphaproteobacteriaLanthanoid Series ElementsMethanolSeawaterAlcohol OxidoreductasesBacterial ProteinsPhylogenyalcohol dehydrogenase (acceptor)Alcohol OxidoreductasesBacterial ProteinsLanthanoid Series ElementsMethanolAlphaproteobacteriadiellanthanidesmarinemetatranscriptomicsmethanolmethanol dehydrogenasemethylotrophyrare earth elementSargasso Sea

Identifiers

PMID40970701
PMCPMC12542740

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.