ArticleThe Laryngoscope2026
Single Platelet Rich Plasma Glottic Injections in Vocal Pathology Demonstrate Long Term Benefits.
Article in The Laryngoscope, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Single Platelet Rich Plasma Glottic Injections in Vocal Pathology Demonstrate Long Term Benefits.The Laryngoscope · 2026Article
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesPlatelet rich plasma (PRP) injection of the vocal folds (VF) is increasingly recognized as beneficial for VF pathologies. We examined how the number of PRP injections impacted voice outcomes in patients with VF pathologies excluding malignancy.
methodsPatients undergoing PRP VF injections were followed prospectively (1, 3, 6, and 12 months) with examination, perceptual ratings, videostroboscopy, and completed questionnaires (Voice Handicap Index-10 [VHI-10], Vocal Fatigue Index [VFI]), rating improvement, and willingness to repeat PRP injection. Patients underwent between 1 and 7 PRP injections under local anesthetic in the office. Comparison of outcomes for single versus multiple doses of PRP was undertaken.
resultsEighty-three individuals (60% female) received 123 PRP injections. Fifty-four participants (65%) had single injections, and 29 had 2-7 injections. Mean difference between pre-injection and 12-month VHI-10 for single and multiple injections was reduction of 6.95 (SD 4.8) and 8.2 (SD 13.4) respectively. There was no statistically significant difference in change in VHI-10 from baseline to 12 months (p = 0.71), 6 months (p = 0.74), or 3 months (p = 0.23) comparing single versus multiple injection groups. There was no difference in "improvement of VHI-10" or VFI between single versus multiple injection groups. Individuals with VF scar or previous procedures were more likely to require more than one PRP injection.
conclusionSingle PRP injection of the VF can provide significant improvement in vocal parameters in individuals with benign VF pathology out to 12 months. Additional PRP injections following an index injection should be considered on a case-by-case basis for patients where initial effects fade or additional benefit is desired. LEVEL OF EVIDENCE: 3:
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