Evidence map›Paper›PMID 40970415›Full record

ArticleMovement disorders clinical practice2026

Prevalence of Parkinson's Disease in a Town of the Central Highlands of Peru: A Population-Based Study.

Elison Sarapura-Castro, Karina Milla-Neyra, Julia Ríos-Pinto, Jorge L Maguiña, Andrea Rivera-Valdivia, Miguel Inca-Martinez, Maryenela Illanes-Manrique, Milagros Galecio-Castillo, Silvia Montano, Ignacio F Mata and 1 more

Abstract read
In one paragraph

Article in Movement disorders clinical practice, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Elison Sarapura-CastroNeurogenetics Working Group, Universidad Cientifica del Sur, Lima, Peru.ORCID https://orcid.org/0000-0002-1562-3062
Karina Milla-NeyraNeurogenetics Research Center, Instituto Nacional de Ciencias Neurologicas, Lima, Peru.ORCID https://orcid.org/0000-0002-7699-4393
Julia Ríos-PintoUniversidad Peruana Los Andes, Huancayo, Peru.ORCID https://orcid.org/0000-0002-7216-1669
Jorge L MaguiñaFacultad de Ciencias de la Salud, Universidad Cientifica del Sur, Lima, Peru.ORCID https://orcid.org/0000-0002-4136-7795
Andrea Rivera-ValdiviaNorthern Pacific Global Health Research Program, NIH, Bethesda, Maryland, USA.ORCID https://orcid.org/0000-0002-3911-9776
Miguel Inca-MartinezGenomic Medicine Institute, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio, USA.ORCID https://orcid.org/0000-0003-3770-0476
Maryenela Illanes-ManriqueNeurogenetics Working Group, Universidad Cientifica del Sur, Lima, Peru.ORCID https://orcid.org/0000-0002-3098-0981
Milagros Galecio-CastilloNeurogenetics Working Group, Universidad Cientifica del Sur, Lima, Peru.ORCID https://orcid.org/0000-0002-8107-9632
Silvia MontanoNaval Medical Research Unit No. 6, Callao, Peru.
Ignacio F MataGenomic Medicine Institute, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio, USA.ORCID https://orcid.org/0000-0003-1198-0633
Mario Cornejo-OlivasNeurogenetics Working Group, Universidad Cientifica del Sur, Lima, Peru.ORCID https://orcid.org/0000-0001-6313-5680

Funding

Additional Sequencing for the Alzheimer Disease Sequencing Project (ADSP) the Follow-Up Study (FUS), The Global Population InitiativeU01AG076482 · NIA · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI Clifton L Dalgard, ANTHONY JOHN GRISWOLD · 2022 to 2026
$26.9M
NPGH LEADERs YR12: OBSSR (Greenberg, Ngwafong Mukere) & NIBIB (Lee)D43TW009345 · FIC · UNIVERSITY OF WASHINGTON · PI Dibyadyuti Datta, Chandy C. John · 2017 to 2026
$15.2M
Modeling the impact of Women's Specific Health Factors in PD outcomes in LatinasR01NS112499 · NINDS · CLEVELAND CLINIC LERNER COM-CWRU · PI FERNANDEZ MATA, IGNACIO · 2020 to 2024
$3.3M
BLRD VA I01 BX005978FIC NIH HHS Award Number D43TW009345FIC NIH HHS D43 TW009345NIA NIH HHS U01 AG076482NINDS NIH HHS R01 NS112499
6 · The paper itself

Abstract

backgroundThe global prevalence of Parkinson's disease (PD) is estimated to be 315 per 100,000 inhabitants, with variations across regions and depending on the epidemiological methods used. Door-to-door prevalence studies in Andean communities are notably underrepresented in the literature.

objectiveThe aim of this study was to estimate the PD prevalence in Jauja.

methodsA cross-sectional community-based door-to-door prevalence study was conducted from April 2018 to September 2019. We used a Spanish version of the 9-item screening questionnaire (9-item SQ). Trained interviewers conducted face-to-face screening surveys. Participants presenting "suspected parkinsonism" underwent further neurological assessment. PD cases responded to the LARGE-PD questionnaire and "pesticide exposure questionnaire." We calculated the crude prevalence, gender- and age-specific rates, and age-adjusted rates.

resultsOut of 2527 eligible individuals, 1960 completed the screening survey. Of these, 563 were selected for neurological assessment, and 337 underwent neurological examination. PD was confirmed in 21 individuals, 16 of whom were identified using the 9-item SQ with a crude prevalence of 816/100,000. We observed higher rates of PD in older age groups and in males compared to females (1.6 vs. 0.3%, P < 0.05). The age-standardized prevalence was 566/100,000 (95% confidence interval [CI]: 496.6-635.2). Among PD cases, the most common environmental exposures were living near farming fields and pesticide exposure.

conclusionsThe observed prevalence of PD in this town in the central highlands of Peru aligns with previous reports, with notably higher rates among individuals over the age of 80. Further prospective studies are warranted to investigate the potential influence of environmental factors on PD prevalence in this region.

Indexed as

Parkinson DiseaseAdultAgedAged, 80 and overCross-Sectional StudiesFemaleHumansMaleMiddle AgedPeruPesticidesPrevalenceSurveys and QuestionnairesYoung AdultPesticidesdoor‐to‐doorhighlandsParkinson's diseaseprevalence

Identifiers

PMID40970415
PMCPMC12919289

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.