Evidence map›Paper›PMID 40970262›Full record

ArticleClinical case reports2025

A Case of Double ANCA-Negative Granulomatosis With Polyangiitis in an Ethiopian Man: A Diagnostic Challenge in a Resource-Limited Setting.

Alazar Sitotaw, Mekoya Mengistu, Ephrem Fantu, Gashaw Solela, Selam Bogale, Amanuel Zeleke, Yoseph Abebe, Mengistu Abate, Abdurahim Wereka, Samuel Befekadu and 4 more

Abstract read
In one paragraph

Article in Clinical case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Alazar SitotawDepartment of Internal Medicine Yekatit 12 Hospital Medical College Addis Ababa Ethiopia.ORCID https://orcid.org/0009-0009-8153-5018
Mekoya MengistuDepartment of Internal Medicine Yekatit 12 Hospital Medical College Addis Ababa Ethiopia.
Ephrem FantuDepartment of Internal Medicine Yekatit 12 Hospital Medical College Addis Ababa Ethiopia.
Gashaw SolelaDepartment of Internal Medicine Yekatit 12 Hospital Medical College Addis Ababa Ethiopia.ORCID https://orcid.org/0000-0002-2233-9270
Selam BogaleDepartment of Internal Medicine Yekatit 12 Hospital Medical College Addis Ababa Ethiopia.
Amanuel ZelekeDepartment of Internal Medicine Yekatit 12 Hospital Medical College Addis Ababa Ethiopia.
Yoseph AbebeDepartment of Internal Medicine Yekatit 12 Hospital Medical College Addis Ababa Ethiopia.
Mengistu AbateDepartment of Internal Medicine Yekatit 12 Hospital Medical College Addis Ababa Ethiopia.
Abdurahim WerekaDepartment of Internal Medicine Yekatit 12 Hospital Medical College Addis Ababa Ethiopia.ORCID https://orcid.org/0009-0009-5985-6384
Samuel BefekaduInfectious disease control Södertörn university Huddinge Sweden.
Brook FanuelDepartment of Internal Medicine Yekatit 12 Hospital Medical College Addis Ababa Ethiopia.ORCID https://orcid.org/0009-0000-9655-9498
Tihitina FanuelDepartment of Internal Medicine Yekatit 12 Hospital Medical College Addis Ababa Ethiopia.
Ermiyas TeferaDepartment of Internal Medicine Yekatit 12 Hospital Medical College Addis Ababa Ethiopia.
Balew AregaDepartment of Internal Medicine Yekatit 12 Hospital Medical College Addis Ababa Ethiopia.ORCID https://orcid.org/0000-0002-4222-8420

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This case highlights the importance of considering ANCA-negative granulomatosis with polyangiitis (GPA) in patients with nonspecific symptoms with multisystem involvement, including pulmonary, skin, and constitutional symptoms, even in the absence of classical serologic markers after ruling out infectious causes mimicking the presentations in resource-limited settings. A multidisciplinary approach and tissue biopsy are crucial for early diagnosis and initiation of treatment, which can significantly improve outcomes.

Indexed as

ANCA‐negative vasculitiscutaneous vasculitisgranulomatosis with polyangiitispulmonary involvement

Identifiers

PMID40970262
PMCPMC12441018

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.