Evidence map›Paper›PMID 40970248›Full record

ArticleNon-coding RNA research2025

miR-129-1-3p down-regulation promotes BAG cochaperone 3 (BAG3)-driven pro-fibrotic processes in primary fibroblasts from patients with recessive dystrophic epidermolysis bullosa.

Rebecca Nobili, Cristina Barbagallo, Marco Ragusa, Jasmine Genovese, Valentina D'Agostino, Andrea Diociaiuti, Daniele Castiglia, Teresa Odorisio, Giovanna Zambruno, May El Hachem and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Non-coding RNA research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Rebecca NobiliGenodermatosis Research Unit, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.
Cristina BarbagalloDepartment of Biomedical and Biotechnological Sciences, University of Catania, Catania, Italy.
Marco RagusaDepartment of Biomedical and Biotechnological Sciences, University of Catania, Catania, Italy.
Jasmine GenoveseGenodermatosis Research Unit, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.
Valentina D'AgostinoGenodermatosis Research Unit, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.
Andrea DiociaiutiGenodermatosis Research Unit and Dermatology Unit, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.
Daniele CastigliaLaboratory of Molecular and Cell Biology, IDI-IRCCS, Rome, Italy.
Teresa OdorisioLaboratory of Molecular and Cell Biology, IDI-IRCCS, Rome, Italy.
Giovanna ZambrunoGenodermatosis Research Unit, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.
May El HachemGenodermatosis Research Unit and Dermatology Unit, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.
Angelo Giuseppe CondorelliGenodermatosis Research Unit, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recessive dystrophic epidermolysis bullosa (RDEB) is a rare and severe skin fragility disease due to loss-of-function mutations in the

Indexed as

AKTCollagen depositionCollagen lattice contraction assaymiRNA profilingMyofibroblastsSkin fibrosis

Identifiers

PMID40970248
PMCPMC12441624

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.