Trial reportJournal of multidisciplinary healthcare2025
Effect of Knee Angle Specific (60°-90°) Combine versus Isolated Kinetic Chain on Post ACL Recovery Outcomes: A Randomized Control Trial.
Trial report in Journal of multidisciplinary healthcare, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
9 authors.
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Abstract
Background: The demand for anterior cruciate ligament (ACL) reconstruction is steadily rising, necessitating a comprehensive post-ACL rehabilitation plan to accelerate recovery. This study explores the comparative effects of Open Kinetic Chain (OKC), Closed Kinetic Chain (CKC), and their combined effect at a specific knee angle (60° to 90°) in post-ACL reconstruction patients. Methodology: This clinical trial was registered in the Iranian Registry of Clinical Trials (IRCT) on 21-04-2020 (Ref# IRCT20200331046903N1) and conducted on 54 post-ACL reconstruction patients, randomly allocated to three groups (OKC, CKC, and Combined KC) using the lottery method. All groups underwent 16-week rehabilitation programs. Outcomes assessed were pain, range of motion (ROM), and knee function using the visual analog scale, goniometer, and Lysholm score, respectively. Statistical analysis was conducted using one-way and repeated measures ANOVA in SPSS-25. Results: The mean age was 27.25±4.16 years and BMI 25.12±4.03 kg/m². All groups showed statistically significant improvement over 16 weeks (p<0.0001). At week 16, mean pain scores were 10.56±4.38 (Group A), 9.78±3.81 (Group B), and 3.28±3.12 (Group C) (p<0.001); ROM improved to 131.83±7.35, 129.22±7.57, and 140.61±6.13, respectively (p=0.001); knee function scores reached 90.78±4.83, 91.67±4.49, and 97.50±2.15, respectively (p=0.001). All outcome measures showed significant main effects of Group and Visit, with large effect sizes and significant Group×Visit interactions. From baseline to week 16, pain decreased by 85% (Group A), 86% (Group B), and 95% (Group C); ROM increased by 73%, 72%, and 90%; knee function improved by 58%, 63%, and 72%, respectively. Conclusion: These findings indicate that the combined kinetic chain approach is most effective in improving ROM, knee function, and pain reduction following ACL reconstruction. Trial Registration: https://irct.behdasht.gov.ir/.
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