Evidence map›Paper›PMID 40970057›Full record

ArticleCureus2025

Downregulation of Toll-Like Receptor Gene Expression Among Hepatitis B Virus-Positive Human Patients.

Tamadhur H Hussein, Ameera Al-Yami, Nabil Mtiraoui, Jawhar Gharbi, Manel Ben M'hadheb

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Tamadhur H HusseinGenomic, Biotechnology and Antiviral Strategies Research Unit (UR1ES30) DNA Analysis and Sequencing Unit of Common Services for Research (USCR-SAG), Institute of Biotechnology, University of Monastir, Monastir, TUN.
Ameera Al-YamiDepartment of Biological Sciences, College of Science, King Faisal University, Al-Ahsa, SAU.
Nabil MtiraouiLaboratory of Human Genome and Multifactorial Diseases (LR12ES07), Faculty of Pharmacy of Monastir, University of Monastir, Monastir, TUN.
Jawhar GharbiDepartment of Biological Sciences, College of Science, King Faisal University, Al-Ahsa, SAU.
Manel Ben M'hadhebDepartment of Biological Sciences, College of Science, King Faisal University, Al-Ahsa, SAU.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background Hepatitis B virus (HBV) chronically infects over several million people, often progressing to severe liver disease. Toll-like receptors (

Indexed as

gene expressiongenotypeshepatitis b virusmrnatoll-like receptors

Identifiers

PMID40970057
PMCPMC12442744

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.