Evidence map›Paper›PMID 40970035›Full record

ArticleCureus2025

Incidence of Dementia in Canada: A National Trend Analysis of Newly Diagnosed Cases.

Oluwatomiwa S Fasoro, Faith C Anyanwu, Ajibola O Jayeola, Okelue E Okobi, Joan O Osaigbovo, Angela C Onojedje, Rukayat O Balogun, Oluchi C Abah, Aimuamwosa Okoro, Chinasa Okeke-Chikelu

Abstract read
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Oluwatomiwa S FasoroClinical Sciences, College of Health Sciences at Obafemi Awolowo University, Ile Ife, NGA.
Faith C AnyanwuCommunity Health and Primary Health Care, Lagos State University Teaching Hospital, Lagos, NGA.
Ajibola O JayeolaGeneral Practice, Ladoke Akintola University of Technology, Ogbomosho, NGA.
Okelue E OkobiFamily Medicine, Larkin Community Hospital Palm Springs Campus, Miami, USA.
Joan O OsaigbovoFamily Medicine, Nnamdi Azikiwe University Teaching Hospital, Nnewi, NGA.
Angela C OnojedjeGeneral Medicine, Madonna University, Ogene, NGA.
Rukayat O BalogunFamily Medicine, South Tyneside and Sunderland NHS Foundation Trust, Sunderland, GBR.
Oluchi C AbahFamily and Community Medicine, Abia State University, Uturu, NGA.
Aimuamwosa OkoroGeneral Medicine, I. Horbachevsky Ternopil National Medical University, Ternopil, UKR.
Chinasa Okeke-ChikeluFaculty of Medicine, Windsor University School of Medicine, Basseterre, KNA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionDementia is a progressive neurocognitive disorder affecting aging populations worldwide. Understanding its incidence trends is essential for planning preventive strategies and healthcare services, particularly in countries with aging demographics like Canada. This study aimed to examine national trends in the age-standardized incidence rates of newly diagnosed dementia, including Alzheimer's disease, among Canadians aged 65 years or older from 2007 to 2022.

methodsWe conducted a retrospective, population-based trend analysis using the Canadian Chronic Disease Surveillance System (CCDSS), administered by the Public Health Agency of Canada (PHAC). The CCDSS aggregates de-identified administrative health data supplied by provincial and territorial health ministries, including physician billing claims, hospital discharge abstracts, and health insurance registry data. Dementia cases were ascertained using validated International Classification of Diseases (ICD)-9/ICD-10 diagnostic codes for Alzheimer's disease and related dementias applied to physician and hospital records (case definition and code list per CCDSS protocols). The study period covered fiscal years 2007-2008 through 2021-2022, with supplementary data for 2022-2023 where available. Age-standardized incidence rates were calculated using the 2011 Canadian standard population. Data completeness for physician billing and hospital discharge records exceeded 95% in participating jurisdictions; however, some provinces/territories had partial or missing submissions in certain years. All analyses used aggregated, de-identified counts provided by CCDSS; no individual-level records were accessed.

resultsIn 2022, the crude incidence rate of newly diagnosed dementia among Canadians aged 65 years and older was 1,323 per 100,000 population per year (95%CI: 1315-1331). By sex, females had a higher crude incidence (1,437 per 100,000 population per year; 95%CI: 1425-1449) than males (1,194 per 100,000 population per year; 95%CI: 1183-1206). Incidence increased markedly with advancing age: 610 per 100,000 population per year (95%CI: 604-617) in those aged 65-79, and 3,669 per 100,000 population per year (95%CI: 3640-3697) among individuals aged more than 80. Regional disparities were observed: Nunavut had the highest age-standardized rate (1,700 per 100,000 population per year; 95%CI: 921-2969) while Saskatchewan had the lowest (1,154 per 100,000 population per year; 95%CI: 1108-1203). From 2007 to 2022, the age-standardized incidence declined overall; this pattern may potentially reflect improvements in prevention, risk-factor control, or early detection, although causal attribution cannot be established from these data alone.

conclusionAlthough the age-standardized incidence of newly diagnosed dementia in Canada declined modestly between 2007 and 2022, substantial sex, age, and regional disparities remain. The findings emphasize the need for ongoing investment in dementia prevention, equitable diagnostic access, and region-specific interventions. With the aging population, coordinated public health strategies remain essential to sustain progress and reduce the future burden of dementia on individuals, caregivers, and healthcare systems.

Indexed as

aging populationalzheimer's diseasecanadadementiaepidemiologyhealthcare planningincidence trendsregional disparities

Identifiers

PMID40970035
PMCPMC12443458

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.