Evidence map›Paper›PMID 40970022›Full record

ArticleCureus2025

Early Diagnosis of Streptococcal Toxic Shock Syndrome With Abdominal Computed Tomography: A Case Report.

Ryo Kurokawa, Mariko Kurokawa, Soma Onoda, Yusuke Onozato, Akihito Nakajima, Tomoki Wada, Osamu Abe

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ryo KurokawaDepartment of Radiology, The University of Tokyo, Tokyo, JPN.
Mariko KurokawaDepartment of Radiology, The University of Tokyo, Tokyo, JPN.
Soma OnodaDepartment of Radiology, The University of Tokyo, Tokyo, JPN.
Yusuke OnozatoDepartment of Radiology, The University of Tokyo, Tokyo, JPN.
Akihito NakajimaDepartment of Radiology, The University of Tokyo, Tokyo, JPN.
Tomoki WadaDepartment of Emergency and Critical Care Medicine, The University of Tokyo, Tokyo, JPN.
Osamu AbeDepartment of Radiology, The University of Tokyo, Tokyo, JPN.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Streptococcal toxic shock syndrome (STSS) is a rapidly progressive and highly lethal infection caused by group A streptococcus, in which early diagnosis remains challenging due to nonspecific initial symptoms. We report a case of a 37-year-old woman who developed severe abdominal pain 24 hours after outpatient cervical polypectomy, with progression to septic shock at 48 hours post-procedure, presenting with hypotension, diffuse erythema, leukopenia, acute kidney injury, and elevated inflammatory markers. Contrast-enhanced abdominal computed tomography (CT) demonstrated pelvic-predominant peritoneal thickening, uniform small-bowel wall thickening with serosal thickening, and mesenteric vascular engorgement, findings suggestive of toxin-mediated peritonitis rather than primary enteritis. Based on clinical presentation and CT findings, invasive group A streptococcal infection with STSS was strongly suspected, prompting immediate treatment with meropenem plus clindamycin and hemodynamic support before obtaining the blood culture result. The next day, blood cultures confirmed

Indexed as

computed tomographygroup a streptococcusgynecologic procedureperitonitisstreptococcal toxic shock syndrome

Identifiers

PMID40970022
PMCPMC12441656

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.