Evidence map›Paper›PMID 40970012›Full record

ArticleCureus2025

Symptomatic Cerebral Vasospasm After Clipping of an Unruptured Intracranial Aneurysm: A Case Report and Literature Review.

Maoki Matsubara, Yoshiki Takizawa, Yuzo Saito, Yoshinobu Sekihara, Norihiro Ishii

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Maoki MatsubaraNeurological Surgery, New Tokyo Hospital, Matsudo, JPN.
Yoshiki TakizawaNeurological Surgery, New Tokyo Hospital, Matsudo, JPN.
Yuzo SaitoNeurological Surgery, New Tokyo Hospital, Matsudo, JPN.
Yoshinobu SekiharaNeurological Surgery, New Tokyo Hospital, Matsudo, JPN.
Norihiro IshiiNeurological Surgery, New Tokyo Hospital, Matsudo, JPN.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Symptomatic cerebral vasospasm after clipping of unruptured intracranial aneurysms (UIA) is extremely rare. Furthermore, its pathophysiology and risk factors are poorly understood. Delayed diagnosis and treatment can lead to severe neurological deficits. We report the case of a 53-year-old woman who developed delayed symptomatic cerebral vasospasm seven days after clipping of an unruptured left middle cerebral artery (MCA) aneurysm. The patient presented with right-sided hemiparesis and motor aphasia. Digital subtraction angiography revealed vasospasms from the M1 to M2 segments. Treatment with intra-arterial fasudil injection and continuous intravenous fasudil with ozagrel sodium resulted in complete neurological recovery. Cerebral vasospasm after UIA clipping is uncommon and may be overlooked, thereby resulting in serious sequelae.

Indexed as

cerebral vasospasmdelayed ischemic neurological deficitintracranial aneurysm growthmicrosurgical aneurysm clippingmiddle cerebral artery infarction

Identifiers

PMID40970012
PMCPMC12441220

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.