Evidence map›Paper›PMID 40969999›Full record

ArticleCureus2025

Unique Presentation of the Follicular Occlusion Tetrad: A Case Report and Review of the Literature.

Robert Adler, Isha Gandhi, Maisha Sheikh, Justin Marson, Steven Fishman

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Robert AdlerDermatology, State University of New York (SUNY) Downstate College of Medicine, New York City, USA.
Isha GandhiMedicine, University of Minnesota Twin Cities Medical School, Minneapolis, USA.
Maisha SheikhDermatology, State University of New York (SUNY) Downstate College of Medicine, New York City, USA.
Justin MarsonDermatology, State University of New York (SUNY) Downstate College of Medicine, New York City, USA.
Steven FishmanDermatology, Mount Sinai Medical Center, New York City, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The follicular occlusion tetrad is a chronic inflammatory complex that consists of four co-related conditions in which follicles are blocked with keratin rupture and lead to inflammation. These conditions include hidradenitis suppurativa (HS), acne conglobata (AC), dissecting cellulitis of the scalp (DCS), and pilonidal cyst (PC). Our unique case reports a 43-year-old female patient who presented with a 36-year history of all four elements of the tetrad after previous treatment with ciprofloxacin, spironolactone, and salicylic acid. Our case is notable as the patient presented after being on semaglutide for weight loss, as well as the first report of the full tetrad in a female patient. A comprehensive review of the follicular occlusion tetrad was conducted using current literature. The goal of the literature review was to provide a general overview of the patient population diagnosed with follicular occlusion tetrad. Additionally, weight loss medications were discussed as potential treatments for patients given the link between the disease and obesity. Further study is warranted to investigate the efficacy of newer therapies in managing patients.

Indexed as

acne conglobatacase reportdissecting cellulitis of scalpfollicular occlusion tetradglp-1 agonisthidradenitis suppurativaliterature reviewpilonidal cyst

Identifiers

PMID40969999
PMCPMC12443365

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.