ArticleCureus2025
Pigment Pathways Collide: A Rare Case of Retinitis Pigmentosa and Nevus of Ota.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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2 authors.
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Abstract
Nevus of Ota (ocular melanosis) is a dermal melanocytosis involving the ophthalmic and maxillary regions and can present with ocular involvement as melanosis oculi. Retinitis pigmentosa (RP) is a hereditary retinal dystrophy characterized by progressive photoreceptor degeneration. We report the first documented rare case of a 59-year-old female patient with a history of treated breast carcinoma who presented for an eye evaluation due to vision loss. Ocular examination revealed bilateral RP and unilateral ocular melanosis (Nevus of Ota). No established syndromic or genetic links between Nevus of Ota and RP exist. While pigmentation disorders such as albinism or syndromes like Waardenburg syndrome may involve both melanin pathways and retinal degeneration, Nevus of Ota has not been associated with retinal dystrophies in the literature. This case explores whether this co-occurrence may suggest a rare, undocumented syndromic association or is merely coincidental.
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