Evidence map›Paper›PMID 40969867›Full record

ArticleJournal of diabetes and metabolic disorders2025

Assessment and outcome of the management of hyperthyroidism in Malaysian primary care clinics: A national multicentre study.

Jazlan Jamaluddin, Aiza Nur Izdihar Zainal-Abidin, Mohd Azzahi Mohamed Kamel, Nik Aminah Nik Abdul Kadir, Mohd Yusaini Mohd Yusri, Nurfauzani Ibrahim, Siti Nur Hidayah Abd Rahim, Nur Athirah Rosli, Nor Shazatul Salwana Din, Nurainee Ibrahim and 1 more

Abstract read
In one paragraph

Article in Journal of diabetes and metabolic disorders, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Jazlan JamaluddinDepartment of Primary Care Medicine, Faculty of Medicine, Universiti Malaya, Kuala Lumpur, Malaysia.ORCID 0000-0002-9745-9736
Aiza Nur Izdihar Zainal-AbidinDepartment of Primary Care Medicine, Faculty of Medicine, Universiti Teknologi MARA, Shah Alam, Selangor Malaysia.ORCID 0000-0002-6491-1378
Mohd Azzahi Mohamed KamelKlinik Kesihatan Lenggong, Ministry of Health Malaysia, Hulu Perak, Perak Malaysia.ORCID 0000-0003-0384-1641
Nik Aminah Nik Abdul KadirKlinik Kesihatan Ijok, Ministry of Health Malaysia, Selangor, Malaysia.ORCID 0009-0008-1573-285X
Mohd Yusaini Mohd YusriKlinik Kesihatan Seremban 2, Ministry of Health Malaysia, Seremban, Negeri Sembilan Malaysia.ORCID 0000-0002-0846-7081
Nurfauzani IbrahimKlinik Kesihatan Jelebu, Ministry of Health Malaysia, Kuala Klawang, Negeri Sembilan Malaysia.
Siti Nur Hidayah Abd RahimKlinik Kesihatan Menggatal, Ministry of Health Malaysia, Kota Kinabalu, Sabah Malaysia.ORCID 0000-0003-0182-1639
Nur Athirah RosliKlinik Kesihatan Tanjung Karang, Ministry of Health Malaysia, Tanjung Karang, Selangor Malaysia.ORCID 0000-0001-7880-3338
Nor Shazatul Salwana DinKlinik Kesihatan Kuala Selangor, Ministry of Health Malaysia, Kuala Selangor, Malaysia.ORCID 0000-0002-2537-4725
Nurainee IbrahimKlinik Kesihatan Putrajaya Presint 18, Ministry of Health Malaysia, Putrajaya, Wilayah Persekutuan Malaysia.
UITM-GRAD Study investigators

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: This study assesses the management of hyperthyroidism in primary care clinics, focusing on adherence to clinical guidelines and resulting treatment outcomes. Methods: This study retrospectively reviews medical records of patients with overt hyperthyroidism attending 11 primary care clinics between 1st January 2023 and 31st December 2023. Patients are identified through laboratory results, electronic medical records, or pharmacy records. Eligible cases include adults diagnosed with overt hyperthyroidism with at least 12 months of follow-up. Data were collected and analysed descriptively. Results: A total of 143 patients were included, with a mean age of 49.0 ± 14.8 years, predominantly female (73.4%) and Malay (81.1%). While 96.5% of cases were correctly diagnosed, documentation of aetiology (52.4%) and treatment counselling (28.7%) was suboptimal. Thyroid function monitoring was inconsistent, with only 52.4% undergoing repeat testing within 2-6 weeks. ATD therapy was appropriately initiated in 65.0% of cases, but side effect counselling was documented in only 11.9%. Within 18 months, 59.4% achieved euthyroidism, and 62.2% avoided iatrogenic hypothyroidism. Conclusion: Despite appropriate diagnosis and treatment initiation, gaps exist in monitoring, documentation, and referrals. Future efforts should focus on strengthening adherence to guidelines and improving patient tracking systems to enhance hyperthyroidism management in primary care.

Indexed as

DiagnosisDisease managementHyperthyroidismMalaysiaPrimary health care

Identifiers

PMID40969867
PMCPMC12440837

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.