Evidence map›Paper›PMID 40969853›Full record

ArticleTechnical innovations & patient support in radiation oncology2025

Standard operating procedure (SOP) for immobilisation, scanning, verification and treatment of breast cancer patients undergoing proton beam therapy.

Kathryn Osborn, Jaymisha Davda, Rita Simoes, Michael O'Connor, Olivia Willis, Sarah Gulliford, Syed Ali Moinuddin, Turmi Patel, Sarah Petty, Mahbubl Ahmed and 2 more

Abstract read
In one paragraph

Article in Technical innovations & patient support in radiation oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Kathryn OsbornProton Beam Therapy department, University College London Hospitals (UCLH) NHS Trust, UK.
Jaymisha DavdaProton Beam Therapy department, University College London Hospitals (UCLH) NHS Trust, UK.
Rita SimoesProton Beam Therapy department, University College London Hospitals (UCLH) NHS Trust, UK.
Michael O'ConnorProton Beam Therapy department, University College London Hospitals (UCLH) NHS Trust, UK.
Olivia WillisProton Beam Therapy department, University College London Hospitals (UCLH) NHS Trust, UK.
Sarah GullifordProton Beam Therapy department, University College London Hospitals (UCLH) NHS Trust, UK.
Syed Ali MoinuddinProton Beam Therapy department, University College London Hospitals (UCLH) NHS Trust, UK.
Turmi PatelProton Beam Therapy department, University College London Hospitals (UCLH) NHS Trust, UK.
Sarah PettyProton Beam Therapy department, University College London Hospitals (UCLH) NHS Trust, UK.
Mahbubl AhmedProton Beam Therapy department, University College London Hospitals (UCLH) NHS Trust, UK.
Thomas RichardsProton Beam Therapy department, University College London Hospitals (UCLH) NHS Trust, UK.
Sairanne WickersProton Beam Therapy department, University College London Hospitals (UCLH) NHS Trust, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The use of proton beam therapy (PBT) for breast cancer is not currently included for standard consideration on the NHS England indication list. However, there are occasions where the use of PBT may be approved in the United Kingdom (UK), such as breast sarcoma, as part of a clinical trial or due to a photon plan meeting a threshold for significant risk of acute and late toxicities (e.g. pre-existing co-morbidities). Due to the beam characteristics, the use of PBT for breast treatment poses challenges in terms of the immobilisation, pre-treatment scanning, treatment verification and delivery. This standard operating procedure (SOP) details strategies to mitigate these that were developed as part of the implementation of breast PBT at our institution. This SOP will support existing and new PBT services when treating this patient cohort, by providing a detailed step-by-step guide to improve consistency and efficiency in the management of breast PBT.

Identifiers

PMID40969853
PMCPMC12441713

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.