Evidence map›Paper›PMID 40969824›Full record

ArticleRSC advances2025

Formulation and characterization of a sortase a inhibitor-loaded PMMA bone cement.

Yin-Yu Qi, Lu-Yang Han, Long-Xu Han, Wen-Han Bu, Yang Xu, Jian-Jun Chu

Abstract read
In one paragraph

Article in RSC advances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yin-Yu QiBengbu Medical University, The Second People's Hospital of Hefei (Affiliated Hospital) Anhui 230011 China chujianj@mail.ustc.edu.cn xuyang@hfut.edu.cn.
Lu-Yang HanBengbu Medical University, The Second People's Hospital of Hefei (Affiliated Hospital) Anhui 230011 China chujianj@mail.ustc.edu.cn xuyang@hfut.edu.cn.
Long-Xu HanBengbu Medical University, The Second People's Hospital of Hefei (Affiliated Hospital) Anhui 230011 China chujianj@mail.ustc.edu.cn xuyang@hfut.edu.cn.
Wen-Han BuBengbu Medical University, The Second People's Hospital of Hefei (Affiliated Hospital) Anhui 230011 China chujianj@mail.ustc.edu.cn xuyang@hfut.edu.cn.
Yang XuBengbu Medical University, The Second People's Hospital of Hefei (Affiliated Hospital) Anhui 230011 China chujianj@mail.ustc.edu.cn xuyang@hfut.edu.cn.ORCID https://orcid.org/0000-0002-8393-6255
Jian-Jun ChuBengbu Medical University, The Second People's Hospital of Hefei (Affiliated Hospital) Anhui 230011 China chujianj@mail.ustc.edu.cn xuyang@hfut.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A sortase A inhibitor (SrtA I)-loaded bone cement (SLBC) containing 1-(3,4-dichlorophenyl)-3-(dimethylamino)propyl-1-one hydrochloride (AEEK1) was reported. Compared with gentamicin-loaded bone cement (GS cement), which is a widely used antibiotic-loaded bone cement in cemented total joint replacement (TJR), SLBC demonstrated a significantly prolonged effective antibacterial duration against both

Identifiers

PMID40969824
PMCPMC12442756

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.