Evidence map›Paper›PMID 40969640›Full record

ArticleFrontiers in public health2025

Global, regional, national burden and trends of unintentional injuries from 1990 to 2021 and projections to 2035: a systematic analysis of the Global Burden of Disease study 2021.

Wenpeng Qin, Xiugen Liu, Jusen Nong, Daqin Feng, Guoshen Liu, Jiaqi Xie, Weicheng Huang, Hao Liang, Linlu Yan, Haojun Tang and 16 more

Abstract read
In one paragraph

Article in Frontiers in public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

26 authors.

Wenpeng Qin *Department of Neurosurgery, The First Affiliated Hospital of Guangxi Medical University, Nanning, China.
Xiugen Liu *Department of Neurosurgery, The First Affiliated Hospital of Guangxi Medical University, Nanning, China.
Jusen Nong *Department of Pediatric Surgery, The First Affiliated Hospital of Guangxi Medical University, Nanning, China.
Daqin Feng *Department of Neurosurgery, The First Affiliated Hospital of Guangxi Medical University, Nanning, China.
Guoshen LiuDepartment of Neurosurgery, The First Affiliated Hospital of Guangxi Medical University, Nanning, China.
Jiaqi XieDepartment of Neurosurgery, The First Affiliated Hospital of Guangxi Medical University, Nanning, China.
Weicheng HuangDepartment of Neurosurgery, The First Affiliated Hospital of Guangxi Medical University, Nanning, China.
Hao LiangDepartment of Neurosurgery, The First Affiliated Hospital of Guangxi Medical University, Nanning, China.
Linlu YanDepartment of Neurosurgery, The First Affiliated Hospital of Guangxi Medical University, Nanning, China.
Haojun TangDepartment of Neurosurgery, The First Affiliated Hospital of Guangxi Medical University, Nanning, China.
Fengjun QinDepartment of Neurosurgery, The First Affiliated Hospital of Guangxi Medical University, Nanning, China.
Fei HuangDepartment of Neurosurgery, The First Affiliated Hospital of Guangxi Medical University, Nanning, China.
Kai FuDepartment of Neurosurgery, The First Affiliated Hospital of Guangxi Medical University, Nanning, China.
Chang LiuGuangxi Medical University, Nanning, China.
Changkai WeiDepartment of Neurosurgery, The First Affiliated Hospital of Guangxi Medical University, Nanning, China.
Bingning YangDepartment of Neurosurgery, The First Affiliated Hospital of Guangxi Medical University, Nanning, China.
Shasha JianDepartment of Neurosurgery, The First Affiliated Hospital of Guangxi Medical University, Nanning, China.
Liping LiuDepartment of Neurosurgery, The First Affiliated Hospital of Guangxi Medical University, Nanning, China.
Jinfeng SuDepartment of Neurosurgery, The First Affiliated Hospital of Guangxi Medical University, Nanning, China.
Ping ZhangDepartment of Neurosurgery, The First Affiliated Hospital of Guangxi Medical University, Nanning, China.
Jialing TangDepartment of Neurosurgery, The First Affiliated Hospital of Guangxi Medical University, Nanning, China.
Jiao ZhuoDepartment of Neurosurgery, The First Affiliated Hospital of Guangxi Medical University, Nanning, China.
Qingtong MoDepartment of Neurosurgery, The First Affiliated Hospital of Guangxi Medical University, Nanning, China.
Chang LiuDepartment of Neurosurgery, The First Affiliated Hospital of Guangxi Medical University, Nanning, China.
Yongjia YuDepartment of Neurosurgery, The First Affiliated Hospital of Guangxi Medical University, Nanning, China.
Lun LiangDepartment of Neurosurgery, The First Affiliated Hospital of Guangxi Medical University, Nanning, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Unintentional injuries, including drowning, falls, and heat-related incidents, constitute a substantial challenge to global health. The present study utilizes data from t the Global Burden of Disease (GBD) database to investigate the burden of unintentional injuries spanning the period from 1990 to 2021. It integrates these findings with future projections and advanced analytical approaches. Methods: Epidemiological data pertaining to unintentional injuries, sourced from the Global Burden of Disease (GBD) database covering the period 1990-2021, were subjected to analysis. This study centered on three core indicators: age-standardised incidence rate (ASIR), age-standardised mortality rate (ASDR), and age-standardised disability-adjusted life years (DALYs). The data were stratified by geographical region and classified in accordance with the Sociodemographic Index (SDI). The analytical approaches employed encompassed the computation of key metrics, trend evaluation, determination of relative variations, as well as the application of sophisticated methodologies for frontier analysis and projections, with all analyses conducted using R software. Results: From 1990 to 2021, the global number of new cases of unintentional injuries rose, while both mortality figures and DALYs cases associated with such injuries trended downward. Age-standardized rates for incidence, mortality, and DALYs also decreased to varying extents. Among level 3 classifications of unintentional injuries based on age-standardized rates, falls imposed the heaviest burden. A robust positive association was identified between ASIR and SDI, in contrast to the strong inverse correlations observed between SDI and both ASDR and age-standardized DALYs rate. Frontier analysis encompassing 204 countries and territories further indicated that age-standardized DALYs rates generally diminished as SDI levels climbed. Projections extending to 2035 suggest that the global downward trajectory will persist for age-standardized indicators, including ASIR, ASDR, and age-standardized DALYs rate. Conclusion: Although ASIR of unintentional injuries decreased between 1990 and 2021, and the burden of such injuries is relatively lighter in regions with a high SDI, notable disparities remain across countries. Sustained scholarly inquiry and innovative healthcare policies are imperative to further alleviate the burden imposed by unintentional injuries.

Indexed as

Accidental InjuriesGlobal Burden of DiseaseGlobal HealthWounds and InjuriesAdolescentAdultAgedChildChild, PreschoolDisability-Adjusted Life YearsFemaleForecastingHumansIncidenceInfantMaleage-standardised disability-adjusted life years (DALYs)age-standardised incidence rate (ASIR)age-standardised mortality rate (ASDR)Global Burden of Disease studypredictionunintentional injuries

Identifiers

PMID40969640
PMCPMC12442766

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