Evidence map›Paper›PMID 40969522›Full record

ArticleRSC advances2025

Piezoelectric electrospun scaffold incorporating ibuprofen loaded ultrasound-responsive mesoporous silica nanoparticles for tissue regeneration.

Alice Benedetto Mas, Jacopo Barberi, Giorgia Montalbano, Silvia Fraterrigo Garofalo, Eleonora Marta, Elsa D Silva, Rita N Gomes, Diana S Nascimento, Sofia Sirolli, Andrea Cafarelli and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in RSC advances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Alice Benedetto MasDepartment of Applied Science and Technology (DISAT), Politecnico di Torino Corso Duca Degli Abruzzi 24 10129 Torino Italy sonia.fiorilli@polito.it.
Jacopo BarberiDepartment of Applied Science and Technology (DISAT), Politecnico di Torino Corso Duca Degli Abruzzi 24 10129 Torino Italy sonia.fiorilli@polito.it.
Giorgia MontalbanoDepartment of Applied Science and Technology (DISAT), Politecnico di Torino Corso Duca Degli Abruzzi 24 10129 Torino Italy sonia.fiorilli@polito.it.
Silvia Fraterrigo GarofaloDepartment of Applied Science and Technology (DISAT), Politecnico di Torino Corso Duca Degli Abruzzi 24 10129 Torino Italy sonia.fiorilli@polito.it.
Eleonora MartaDepartment of Applied Science and Technology (DISAT), Politecnico di Torino Corso Duca Degli Abruzzi 24 10129 Torino Italy sonia.fiorilli@polito.it.ORCID https://orcid.org/0009-0003-8186-5523
Elsa D Silvai3S - Institute for Research and Innovation in Health, University of Porto Porto Portugal dsn@i3s.up.pt.
Rita N Gomesi3S - Institute for Research and Innovation in Health, University of Porto Porto Portugal dsn@i3s.up.pt.
Diana S Nascimentoi3S - Institute for Research and Innovation in Health, University of Porto Porto Portugal dsn@i3s.up.pt.
Sofia SirolliThe BioRobotics Institute, Scuola Superiore Sant'Anna Piazza Martiri della Libertà 33 56127 Pisa Italy.
Andrea CafarelliThe BioRobotics Institute, Scuola Superiore Sant'Anna Piazza Martiri della Libertà 33 56127 Pisa Italy.
Sonia FiorilliDepartment of Applied Science and Technology (DISAT), Politecnico di Torino Corso Duca Degli Abruzzi 24 10129 Torino Italy sonia.fiorilli@polito.it.ORCID https://orcid.org/0000-0002-2986-0528
Chiara Vitale-BrovaroneDepartment of Applied Science and Technology (DISAT), Politecnico di Torino Corso Duca Degli Abruzzi 24 10129 Torino Italy sonia.fiorilli@polito.it.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Inflammation plays a pivotal role in tissue repair, and its modulation is crucial to avoid excessive immune activation or suppression. Three-dimensional scaffolds that can control the release of anti-inflammatory agents over time and space offer a promising approach to regulate the immune response while providing structural support during healing. In this study, we developed an electrospun biomimetic scaffold incorporating ibuprofen-loaded mesoporous silica nanoparticles with an ultrasound-responsive alginate coating. Optimal parameters for safe and non-invasive ultrasound stimulation (

Identifiers

PMID40969522
PMCPMC12442029

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.