Evidence map›Paper›PMID 40969453›Full record

ArticleReproductive medicine and biology

Perspectives on Preimplantation Genetic Testing for Monogenic Disorders Among Japanese Patients With Hereditary Breast Cancer Undergoing Fertility Preservation: Insights From the First Japanese Survey.

Haruhisa Konishi, Yoshiharu Nakaoka, Anmae Michiko, Sho Fujiwara, Rie Kitayama, Daisuke Kadogami, Naoharu Morimoto, Kanako Katsu, Satoko Fujioka, Tomoko Inoue and 3 more

Abstract read
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In one paragraph

Article in Reproductive medicine and biology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Haruhisa KonishiIVF Namba Clinic Osaka Japan.ORCID https://orcid.org/0000-0002-8797-1373
Yoshiharu NakaokaIVF Namba Clinic Osaka Japan.
Anmae MichikoIVF Namba Clinic Osaka Japan.
Sho FujiwaraIVF Namba Clinic Osaka Japan.
Rie KitayamaIVF Namba Clinic Osaka Japan.
Daisuke KadogamiIVF Namba Clinic Osaka Japan.
Naoharu MorimotoIVF Namba Clinic Osaka Japan.
Kanako KatsuIVF Namba Clinic Osaka Japan.
Satoko FujiokaIVF Osaka Clinic Osaka Japan.
Tomoko InoueHORAC GRANDFRONT IVF Osaka Clinic, Grand Front Osaka Tower B Osaka Japan.
Aisaku FukudaIVF Osaka Clinic Osaka Japan.
Hiroki KurahashiIVF Namba Clinic Osaka Japan.ORCID https://orcid.org/0000-0002-5690-5218
Yoshiharu MorimotoHORAC GRANDFRONT IVF Osaka Clinic, Grand Front Osaka Tower B Osaka Japan.ORCID https://orcid.org/0000-0003-2834-2726

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: Preimplantation genetic testing for monogenic disorders (PGT-M) offers Methods: A questionnaire-based survey was administered to 264 patients with breast cancer who were eligible for oocyte or embryo cryopreservation at in vitro fertilization clinics between October 2024 and March 2025. A total of 161 valid responses were analyzed. The survey assessed Results: The uptake rate of Conclusion: These findings highlight the importance of expanding reproductive options and patient awareness of PGT-M in the care of patients with hereditary cancer. Discussions should focus on how best to provide accurate information and enable informed reproductive choices for those at genetic risk.

Indexed as

adolescent and young adult populationsBRCA1/2fertility preservationpreimplantation genetic testingreproductive‐decision‐making

Identifiers

PMID40969453
PMCPMC12441926

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.