Evidence map›Paper›PMID 40969451›Full record

ReviewCochrane evidence synthesis and methods2025

Certainty of evidence assessment in high-impact medical journals: A meta-epidemiological survey.

Madelin R Siedler, Neha Tangri, Leena AlShenaiber, Tejanth Pasumarthi, Faisal Shaukat Ali, Volf Gaby, Katie N Harris, Yngve Falck-Ytter, Reem A Mustafa, Shahnaz Sultan and 3 more

Abstract readReview
In one paragraph

Review in Cochrane evidence synthesis and methods, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Madelin R SiedlerEvidence Foundation Cleveland Heights Ohio USA.ORCID 0000-0002-2845-8174
Neha TangriEvidence Foundation Cleveland Heights Ohio USA.
Leena AlShenaiberEvidence Foundation Cleveland Heights Ohio USA.
Tejanth PasumarthiEvidence Foundation Cleveland Heights Ohio USA.ORCID https://orcid.org/0009-0003-7681-7033
Faisal Shaukat AliDepartment of Gastroenterology, Hepatology and Nutrition The University of Texas Health Science Center Houston Texas USA.ORCID https://orcid.org/0000-0001-7372-5158
Volf GabyEvidence Foundation Cleveland Heights Ohio USA.
Katie N HarrisDepartment of Kinesiology and Sport Management Texas Tech University Lubbock Texas USA.
Yngve Falck-YtterEvidence Foundation Cleveland Heights Ohio USA.
Reem A MustafaEvidence Foundation Cleveland Heights Ohio USA.ORCID https://orcid.org/0000-0002-2091-0875
Shahnaz SultanEvidence Foundation Cleveland Heights Ohio USA.
Philipp DahmEvidence Foundation Cleveland Heights Ohio USA.ORCID https://orcid.org/0000-0003-2819-2553
M Hassan MuradEvidence Foundation Cleveland Heights Ohio USA.ORCID 0000-0001-5502-5975
Rebecca L MorganEvidence Foundation Cleveland Heights Ohio USA.ORCID https://orcid.org/0000-0002-1012-4897

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: While certainty of evidence assessment is key to a rigorous and transparent systematic review, it is unknown how - and how frequently - it is assessed in systematic reviews. The objective of this study was to examine the prevalence and approaches used for certainty of evidence assessment in systematic reviews published in high-impact medicine journals over the past 11 years. Methods: A PubMed search and hand-searching of relevant journal websites identified systematic reviews published between 24 January 2013 and 23 January 2024 in any of the ten highest-impact journals in the General and Internal Medicine category of the Journal Citation Report. Two reviewers independently selected any systematic review related to health outcomes assessing certainty of evidence using any method. We extracted data related to review characteristics, certainty of evidence and risk of bias/methodological quality assessment frameworks, and reported consideration of certainty of evidence domains. Logistic regression examined year of publication to determine whether the prevalence of certainty of evidence assessment changed over time. Results: Of 1,023 included reviews, 346 (33.8%) assessed certainty of evidence. Prevalence of certainty of evidence assessment increased over time (0.16 ± 0.2; Conclusion: Only one in three systematic reviews published in the highest-impact medical journals over the past 11 years assessed certainty of evidence, though prevalence increased over time. The use of specific domains within each certainty of evidence framework was not clearly described in all reviews.

Indexed as

certainty of evidenceevidence‐based medicineGRADEsystematic reviews

Identifiers

PMID40969451
PMCPMC12442678

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.