Evidence map›Paper›PMID 40969439›Full record

ArticleFrontiers in microbiology2025

Molecular characterization of carbapenem-resistant and carbapenem-sensitive

Xinwei Chen, Yanye Tu, Feng Wang, Hong Li, Yujie Zhao, Min Jiang, Hui Gao, Wei Zhang

Abstract read
In one paragraph

Article in Frontiers in microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Genomic characterization of carbapenem-resistantFrontiers in cellular and infection microbiology · 2026
    Article
  3. Comparative genomic insights into carbapenem-resistant versus susceptibleFrontiers in cellular and infection microbiology · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Xinwei ChenDepartment of Clinical Laboratory, The Affiliated Li Huili Hospital of Ningbo University, Ningbo, Zhejiang, China.
Yanye TuDepartment of Clinical Laboratory, The Affiliated Li Huili Hospital of Ningbo University, Ningbo, Zhejiang, China.
Feng WangDepartment of Clinical Laboratory, The Affiliated Li Huili Hospital of Ningbo University, Ningbo, Zhejiang, China.
Hong LiDepartment of Clinical Laboratory, The Affiliated Li Huili Hospital of Ningbo University, Ningbo, Zhejiang, China.
Yujie ZhaoDepartment of Clinical Laboratory, The Affiliated Li Huili Hospital of Ningbo University, Ningbo, Zhejiang, China.
Min JiangDepartment of Clinical Laboratory, The Affiliated Li Huili Hospital of Ningbo University, Ningbo, Zhejiang, China.
Hui GaoDepartment of Clinical Laboratory, The Affiliated Li Huili Hospital of Ningbo University, Ningbo, Zhejiang, China.
Wei ZhangDepartment of Clinical Laboratory, The Affiliated Li Huili Hospital of Ningbo University, Ningbo, Zhejiang, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: This study aims to examine the variations in resistance genes, virulence genes, and drug susceptibility between carbapenem-resistant and carbapenem-susceptible Methods: A retrospective study was undertaken involving 39 Results: The CR-AB isolates demonstrated substantial resistance to ceftazidime, cefepime, ceftriaxone, ampicillin/sulbactam, tobramycin, gentamicin, and levofloxacin, while exhibiting moderate resistance to trimethoprim-sulfamethoxazole and amikacin. Conversely, the CS-AB isolates remained susceptible to all the aforementioned commonly utilized clinical antibiotics. Antimicrobial susceptibility testing indicated that 2.56% of the 39 Conclusion: The CR-AB isolates from the ICU in Ningbo demonstrate heightened resistance and virulence traits in comparison to the CS-AB isolates. The application of the efflux pump inhibitor PAβN markedly increases the susceptibility of CR-AB to ceftazidime/avibactam.

Indexed as

carbapenem-resistant Acinetobacter baumanniiefflux pump inhibitorintensive care unitresistance genesvirulence genes

Identifiers

PMID40969439
PMCPMC12440978

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.