Evidence map›Paper›PMID 40969435›Full record

ReviewFrontiers in microbiology2025

Diagnosis of nontuberculous mycobacterial infections using genomics and artificial intelligence-machine learning approaches: scope, progress and challenges.

Madhan Kumar Murthy, Vivek Kumar Gupta, Anand Prakash Maurya

Abstract readReview
In one paragraph

Review in Frontiers in microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Current Perspectives onInternational journal of molecular sciences · 2026
    Review
  2. Article
  3. Review
  4. [Pulmonary disease caused byZhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2026
    Review
  5. Review
  6. Non-tubercular mycobacterial infections: Emerging from the shadows.Lung India : official organ of Indian Chest Society · 2026
    Article
  7. Article
  8. Understanding recurrence inJournal of clinical microbiology · 2026
    Review
  9. Review
  10. Review
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Madhan Kumar Murthy *Department of Immunology, ICMR-National JALMA Institute for Leprosy and Other Mycobacterial Diseases (ICMR-NJIL&OMD), Agra, Uttar Pradesh, India.
Vivek Kumar GuptaDepartment of Biochemistry, ICMR-National JALMA Institute for Leprosy and Other Mycobacterial Diseases (ICMR-NJIL&OMD), Agra, Uttar Pradesh, India.
Anand Prakash Maurya *Department of Clinical Trials and Implementation Research, ICMR-National JALMA Institute for Leprosy and Other Mycobacterial Diseases (ICMR-NJIL&OMD), Agra, Uttar Pradesh, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The nontuberculous mycobacterial (NTM) infections cause morbidity and mortality in individuals who are immunocompromised and those with lung conditions. The timely diagnosis of NTM infections is thus the need of the hour for appropriate management of the disease. In this context, genomics has played a pivotal role in diagnosis of NTM by targeting various conserved regions which are useful for species identification and diagnosis. Also, the exploring of whole genome of nontuberculous mycobacteria has made species identification easier and has revolutionized the diagnostic landscape of NTM. The refinement of Whole Genome Sequencing (WGS) and the advent of targeted Next Generation Sequencing (tNGS) and metagenomic NGS (mNGS) has helped in bringing down the cost without compromising the quality in NTM diagnostics. The advent of artificial intelligence (AI) technologies has made NTM diagnosis even easier by analyzing complex genomic data and providing faster results. Thus, this comprehensive review discusses the strides made in genomics and AI based approaches in the diagnosis of NTM infections and the way forward for harnessing this potential to the maximum for the benefit of mankind.

Indexed as

artificial intelligencediagnosisgenomicsmachine learningmetagenomic next generation sequencingnext generation sequencingnon tuberculous mycobacteriatargeted next generation

Identifiers

PMID40969435
PMCPMC12440979

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.