Evidence map›Paper›PMID 40969418›Full record

ArticleAvicenna journal of phytomedicine

Inhibition of mast cell activation via MRGPRX2 receptor by

Muhammad Novrizal Abdi Sahid, Masaki Mogi, Kazutaka Maeyama

Abstract read
In one paragraph

Article in Avicenna journal of phytomedicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Muhammad Novrizal Abdi SahidDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, Universitas Gadjah Mada, Sekip Utara, Yogyakarta 55281, Indonesia.
Masaki MogiDepartment of Pharmacology, Graduate School of Medicine, Ehime University, Toon-shi, Ehime 791-0295, Japan.
Kazutaka MaeyamaDepartment of Pharmacology, Graduate School of Medicine, Ehime University, Toon-shi, Ehime 791-0295, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Traditional medicine is often used to relief pain, but its use is frequently not supported by appropriate scientific information. This study aims to investigate the histamine release suppression of Materials and Methods: Rat peritoneal mast cells (RPMCs) and Results: At a concentration of 10 mg/ml, CM resulted in 22.60±5.86% in a spontaneous histamine release from RPMCs. The net histamine release after compound 48/80 stimulation in RPMC was 67.19±1.31%. CM at 3 mg/ml suppressed histamine release to 8.45±2.53%. In Conclusion: SA and CM water suspension suppressed compound 48/80-induced histamine release.

Indexed as

HistamineMRGPRX2-transfected RBL-2H3 cellsPainRat peritoneal mast cellsTraditional medicine

Identifiers

PMID40969418
PMCPMC12441196

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.