ArticleFrontiers in endocrinology2025
Preoperative serum indicators as predictors of postoperative hypoparathyroidism following thyroidectomy.
Article in Frontiers in endocrinology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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Who cites it
1 citing paper in PubMed.
- Standardizing the reporting of postoperative hypoparathyroidism following thyroidectomy: consensus statement from the European Society of Endocrine Surgeons, the American Association of Endocrine Surgeons, and the International Association of Endocrine Surgeons.The British journal of surgery · 2025Article
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7 authors.
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Abstract
Background: Hypoparathyroidism is a frequent complication following thyroidectomy. However, the risk factors for postoperative hypoparathyroidism remain poorly characterized. This study aims to investigate routine clinical characteristics to identify predictors of postoperative hypoparathyroidism. Methods: A retrospective analysis was conducted on 3,638 patients who underwent total or hemithyroidectomy with isthmusectomy through open surgery with routine central lymph node dissection. Based on postoperative serum parathyroid hormone(PTH) levels, patients were subdivided according to the normal reference PTH levels or the Q3 quartile of PTH decline rate. Spearman correlation analysis and stepwise multiple linear regression were used to identify factors affecting preoperative serum PTH levels. Univariate and multivariate logistic regression analyses were performed to explore risk factors for postoperative hypoparathyroidism. Results: Among patients developed postoperative hypoparathyroidism. Multivariate logistic regression revealed that Hashimoto's thyroiditis (HT) ( Conclusions: This study demonstrates that preoperative high glucose levels and HT are risk factors for hypoparathyroidism after total thyroidectomy, while BMI≥24 serves as a protective factor against postoperative hypoparathyroidism. Additionally, female is a risk factor for hypoparathyroidism after both total thyroidectomy and hemithyroidectomy with isthmusectomy, while higher hemoglobin levels and HDL-C are negatively correlated with the decline in PTH levels after total thyroidectomy.
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