Evidence map›Paper›PMID 40969255›Full record

ArticleFrontiers in oncology2025

Case Report: Genomic insights into prostate adenocarcinoma transdifferentiation to carcinosarcoma due to lineage plasticity.

Tomohiro Fukui, Arinobu Fukunaga, Yuki Teramoto, Maki Fujiwara, Kensuke Hikami, Takuro Sunada, Kei Mizuno, Yuki Kita, Takayuki Sumiyoshi, Takayuki Goto and 3 more

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Tomohiro FukuiDepartment of Urology, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Arinobu FukunagaDepartment of Urology, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Yuki TeramotoDepartment of Diagnostic Pathology, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Maki FujiwaraDepartment of Urology, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Kensuke HikamiDepartment of Urology, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Takuro SunadaDepartment of Urology, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Kei MizunoDepartment of Urology, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Yuki KitaDepartment of Urology, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Takayuki SumiyoshiDepartment of Urology, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Takayuki GotoDepartment of Urology, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Ryoichi SaitoDepartment of Urology, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Takashi KobayashiDepartment of Urology, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Shusuke AkamatsuDepartment of Urology, Kyoto University Graduate School of Medicine, Kyoto, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In prostate cancer, it is recognized that adenocarcinoma can transdifferentiate into neuroendocrine prostate cancer (NEPC) owing to lineage plasticity; however, transdifferentiation into other histological types remains uncertain. We present a case of a patient who underwent surgery for adenocarcinoma, which later recurred as prostate carcinosarcoma. Genomic analysis revealed a

Indexed as

carcinosarcomacase reportgenomic analysislineage plasticityprostate cancertransdifferentiation

Identifiers

PMID40969255
PMCPMC12440786

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