ArticleLaryngoscope investigative otolaryngology2025
Charlson-Deyo Index Impact on Overall Survival After Surgery for Sinonasal Squamous Cell Carcinoma.
Article in Laryngoscope investigative otolaryngology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
4 citing papers in PubMed.
- Article
- Comment on "Early versus delayed postoperative extubation after elective neurosurgical treatment of brain metastasis".Journal of cancer research and clinical oncology · 2026Article
- Charlson-Deyo Index Impact on Overall Survival After Surgery for Sinonasal Squamous Cell Carcinoma.Laryngoscope investigative otolaryngology · 2025Article
- Medicare Reimbursement Trends in Zenker's Diverticulectomy.Laryngoscope investigative otolaryngology · 2025Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objectives: Objective preoperative risk assessment tools inform physician and patient decision making. Our study examines the relationship between the Charlson-Deyo comorbidity index (CCI) and overall survival (OS) following surgery for sinonasal squamous cell carcinoma (SNSCC). Methods: In a retrospective cohort study, the 2004-2016 National Cancer Database was used to extract adult patients with pT1-4N0-3 M0 SNSCC undergoing surgery. Kaplan-Meier survival analysis and Cox-proportional hazards modeling were used to analyze the impact of CCI on OS. Results: Of the 3307 patients satisfying inclusion criteria, 2613 (79.0%) were CCI = 0, 533 (16.1%) were CCI = 1, and 161 (4.9%) were CCI = 2+. On univariate analysis, CCI groups differed by age (42.8% were ≥ 65 years old in CCI = 0 vs. 53.3% and 64.0% in CCI groups 1 and 2+, respectively, Conclusions: In a cohort of adult patients with SNSCC undergoing surgery, higher CCI was independently associated with worse OS. These findings support the use of CCI as a predictor of postoperative outcomes in SNSCC patients. Future studies should explore how comorbidity burden interacts with frailty and other prognostic factors to refine risk stratification tools. Level of Evidence: 4.
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