Evidence map›Paper›PMID 40969186›Full record

ArticleACS catalysis2024

Tunable Divergent Reactivity of Aziridinium Ylides in the Synthesis of Complex Piperidines and Azetidines.

Mahzad Dehghany, Giuliana Pavaneli, Jacob W Kailing, Olivia M Duke, Ilia A Guzei, Caroline Da Ros Montes D'Oca, Israel Fernández, Jennifer M Schomaker

Abstract read
In one paragraph

Article in ACS catalysis, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Mahzad DehghanyDepartment of Chemistry, University of Wisconsin, Madison, Wisconsin 53706, United States.
Giuliana PavaneliDepartment of Chemistry, Federal University of Paraná, Curitiba 81530-000, Brazil.
Jacob W KailingDepartment of Chemistry, University of Wisconsin, Madison, Wisconsin 53706, United States.
Olivia M DukeDepartment of Chemistry, University of Wisconsin, Madison, Wisconsin 53706, United States.ORCID 0000-0001-7857-3640
Ilia A GuzeiDepartment of Chemistry, University of Wisconsin, Madison, Wisconsin 53706, United States.ORCID 0000-0003-1976-7386
Caroline Da Ros Montes D'OcaDepartment of Chemistry, Federal University of Paraná, Curitiba 81530-000, Brazil.
Israel FernándezDepartamento de Química Orgánica I and Centro de Innovación en Química Avanzada (ORFEO-CINQA), Facultad de Ciencias Químicas, Universidad Complutense de Madrid, Madrid 28040, Spain.
Jennifer M SchomakerDepartment of Chemistry, University of Wisconsin, Madison, Wisconsin 53706, United States.ORCID 0000-0003-1329-950X

Funding

Versatile complex amine synthesis via aziridinium ylides and 2-amidoallyl cationsR01GM132300 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI SCHOMAKER, JENNIFER MARIE · 2019 to 2022
$1.5M
Harnessing divergent reactivities of unusual reactive intermediates as platforms to explore high Fsp3 amine chemical spaceR35GM152043 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI Jennifer Marie Schomaker · 2024 to 2026
$1.3M
QExactive (Orbitrap) mass spectrometerS10OD020022 · OD · UNIVERSITY OF WISCONSIN-MADISON · PI VESTLING, MARTHA M · 2015 to 2015
$483k
NMR SPECTROMETERS10RR008389 · NCRR · UNIVERSITY OF WISCONSIN MADISON · PI VEDEJS, EDWIN · 1993 to 1993
–
NCRR NIH HHS S10 RR008389NIGMS NIH HHS R01 GM132300NIGMS NIH HHS R35 GM152043NIH HHS S10 OD020022
6 · The paper itself

Abstract

Nitrogenated heterocycles comprise the cores of a number of synthetically useful compounds, including pharmaceuticals, bioactive natural products, agrochemicals, and other drug-like molecules. The widespread interest in methods to increase the fraction of sp

Indexed as

azetidineaziridineaziridinium ylidedehydropiperidineselectivity controltunabilityvinyl carbene

Identifiers

PMID40969186
PMCPMC12443366

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.