Evidence map›Paper›PMID 40969132›Full record

ArticleHistology and histopathology2026

Discordance of intrinsic subtype between primary tumor and lymph node metastasis in breast cancer patients.

Yoko Omi, Tomoko Yamamoto, Yoji Nagashima, Takako Kamio, Kiyomi Horiuchi, Takahiro Okamoto

Abstract read
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Article in Histology and histopathology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yoko OmiDepartment of Endocrine Surgery, Tokyo Women's Medical University, Kawada-cho, Shinjuku-ku, Tokyo. eguro.yoko@twmu.ac.jp.
Tomoko YamamotoDepartment of Surgical Pathology, Tokyo Women's Medical University, Kawada-cho, Shinjuku-ku, Tokyo.
Yoji NagashimaDepartment of Surgical Pathology, Tokyo Women's Medical University, Kawada-cho, Shinjuku-ku, Tokyo.
Takako KamioDepartment of Breast Surgery, Tokyo Women's Medical University, Kawada-cho, Shinjuku-ku, Tokyo.
Kiyomi HoriuchiDepartment of Endocrine Surgery, Tokyo Women's Medical University, Kawada-cho, Shinjuku-ku, Tokyo.
Takahiro OkamotoDepartment of Endocrine Surgery, Tokyo Women's Medical University, Kawada-cho, Shinjuku-ku, Tokyo.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The heterogeneity of cancer cells between primary breast tumors and lymph node (LN) metastases at the initial therapy remains unclear. This study aimed to determine whether intrinsic subtypes of LN metastasis differ from those of primary breast tumors and how much additional information is obtained. Ninety-three breast cancer cases with LN metastasis were enrolled in the study. Immunohistochemistry for ER, PgR, HER2, and Ki-67 was performed for primary breast tumors and the largest LN metastases. The intrinsic subtype was determined as luminal A (ER

Indexed as

Breast NeoplasmsLymphatic MetastasisAdultAgedAged, 80 and overBiomarkers, TumorErb-b2 Receptor Tyrosine KinasesFemaleHumansImmunohistochemistryKi-67 AntigenLymph NodesMiddle AgedReceptors, EstrogenReceptors, ProgesteroneBiomarkers, TumorERBB2 protein, humanErb-b2 Receptor Tyrosine KinasesKi-67 AntigenReceptors, EstrogenReceptors, Progesterone

Identifiers

PMID40969132

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.