Evidence map›Paper›PMID 40969042›Full record

ArticleSensors (Basel, Switzerland)2025

Design and Application of a Radiofrequency Spectrophotometry Sensor for Measuring Esophageal Liquid Flow to Detect Gastroesophageal Reflux.

Pedro J Fito, Ricardo J Colom, Rafael Gadea-Girones, Jose M Monzo, Angel Tebar-Ruiz, F Javier Puertas, Marta Castro-Giraldez

Abstract read
In one paragraph

Article in Sensors (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Pedro J FitoInstituto Universitario de Ingeniería de Alimentos FoodUPV, Universitat Politècnica de València, Camino de Vera s/n, 46022 Valencia, Spain.ORCID 0000-0001-9666-276X
Ricardo J ColomInstituto de Instrumentación para Imagen Molecular I3M, Universitat Politècnica de València, Camino de Vera s/n, 46022 Valencia, Spain.ORCID 0000-0003-0704-4906
Rafael Gadea-GironesInstituto de Instrumentación para Imagen Molecular I3M, Universitat Politècnica de València, Camino de Vera s/n, 46022 Valencia, Spain.ORCID 0000-0003-2857-8667
Jose M MonzoInstituto de Instrumentación para Imagen Molecular I3M, Universitat Politècnica de València, Camino de Vera s/n, 46022 Valencia, Spain.ORCID 0000-0001-6554-3231
Angel Tebar-RuizInstituto de Instrumentación para Imagen Molecular I3M, Universitat Politècnica de València, Camino de Vera s/n, 46022 Valencia, Spain.
F Javier PuertasNeurophysiology and Sleep Unit, La Ribera University Hospital-FISABIO, 46600 Alzira, Spain.ORCID 0000-0002-9341-8160
Marta Castro-GiraldezInstituto Universitario de Ingeniería de Alimentos FoodUPV, Universitat Politècnica de València, Camino de Vera s/n, 46022 Valencia, Spain.ORCID 0000-0001-9360-6869

Funding

Agencia Estatal de Investigación AGL2016-80643-R
6 · The paper itself

Abstract

Gastroesophageal reflux disease (GERD) is a widespread condition that requires reliable and non-invasive diagnostic methods to minimize patient discomfort. This study presents a radiofrequency spectrophotometry sensor specifically designed to detect esophageal liquid flow and ionicity in real time without disrupting the patient's daily life. The sensor operates by measuring dielectric properties and ionic conductivity through the thoracic plexus, eliminating the need for invasive probes or prolonged monitoring. A study conducted on 49 participants demonstrated the sensor's ability to differentiate between various liquid media and identify beta dispersion relaxation as a biomarker for esophageal tissue damage, a key indicator of GERD progression. Additionally, alpha dispersion conductivity effectively distinguished reflux episodes, proving the sensor's high sensitivity. Unlike traditional diagnostic techniques such as endoscopy or pH monitoring, this radiofrequency spectrophotometry sensor enables continuous, real-time reflux detection, allowing patients to maintain a normal lifestyle during assessment. The results validate its potential as an innovative alternative for GERD diagnosis and monitoring, with future research focused on clinical validation, optimization, and integration into long-term patient monitoring systems.

Indexed as

Biosensing TechniquesEsophagusGastroesophageal RefluxAdultEsophageal pH MonitoringFemaleHumansMaleRadio WavesSpectrophotometrybioimpedanceGERDradiofrequency spectroscopyreflux

Identifiers

PMID40969042
PMCPMC12158313

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.