Evidence map›Paper›PMID 40968827›Full record

ArticleSensors (Basel, Switzerland)2025

A Zinc Oxide Interconnected Hydroxypropyl-Beta-Cyclodextrin/rGO Nanocomposite as an Electrocatalyst for Melatonin Detection: An Ultra-Sensitive Electrochemical Sensor.

Kuo-Yuan Hwa, Aravindan Santhan, Chun-Wei Ou, Cheng-Han Wang

Abstract read
In one paragraph

Article in Sensors (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Kuo-Yuan HwaDepartment of Molecular Science and Engineering, National Taipei University of Technology, Taipei 10608, Taiwan.ORCID 0000-0003-1968-7909
Aravindan SanthanDepartment of Molecular Science and Engineering, National Taipei University of Technology, Taipei 10608, Taiwan.
Chun-Wei OuGraduate Institute of Organic and Polymeric Materials, National Taipei University of Technology, Taipei 10608, Taiwan.
Cheng-Han WangGraduate Institute of Organic and Polymeric Materials, National Taipei University of Technology, Taipei 10608, Taiwan.

Funding

Ministry of Science and Technology, Taiwan MOST 113-2221-E-027-014
6 · The paper itself

Abstract

Nanocomposite hydroxypropyl-beta-cyclodextrin functionalized reduced graphene oxide sheets (HpβCD@rGOs) with zinc oxide flaky structures (ZnOFs) were synthesized. The ZnOFs/HpβCD@rGOs were first characterized to examine their physicochemical characteristics. The ZnOFs exhibited a highly crystalline structure intertwined with HpβCD@rGO sheets. The electrocatalyst experienced excellent electrochemical oxidation current responses toward melatonin (MTN). The interaction between the catalyst and MTN improves electrochemical activity through a synergistic action, which can be measured by a glassy carbon electrode (GCE) modified with ZnOFs/HpβCD@rGOs. This modified electrode with the increased reactive sites and a large electrochemically active surface area allows the rapid oxidation reaction of MTN. The oxidation of MTN was detected and measured with a linearity range around 0.014-0.149 and 1.149-643.341 (µM), with a low detection limit (LOD) of around 0.0105 µM or 10.5 nM. The sensitivity was around 6.19 μA μM

Indexed as

biological sampleselectrochemical sensinghydroxypropyl-beta-cyclodextrin@rGOmelatoninzinc oxide flaky structures

Identifiers

PMID40968827
PMCPMC12157216

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.