ReviewInternational journal of surgery (London, England)2026
The bibliometric and visualized analysis on cancer stem cells in the early 21st century.
Review in International journal of surgery (London, England), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed, 1 synthesis or guideline pooled it.
- Ischemic stroke-specific cognitive dysfunction: a bibliometric analysis of research evolution.Frontiers in neurology · 2026Pooled it
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cancer stem cells (CSCs) are a crucial tumor subpopulation, involved in tumor initiation, metastasis and recurrence due to their unique abilities for self-renewal and differentiation. This bibliometric analysis aims to illustrate the current landscape of CSC research from 2001 to 2024, using data from the Web of Science Core Collection. We examined 20 839 publications, analyzing trends in annual publications, author contributions, institutional contributions and keyword co-occurrence. Our findings revealed a rising trend in research output, with the United States and China leading in publication volume. The top two institutions were Sun Yat-sen University and the University of Texas MD Anderson Cancer Center, with Harvard University having the highest average citations. Furthermore, keyword analysis identified major thematic clusters, including (1) Cluster 1 focused on the CSCs biomarkers and drug resistance. (2) Cluster 2 focused on the metabolism of CSCs, including oxidative stress, apoptosis, autophagy, the cell cycle and angiogenesis. (3) Cluster 3 focused on CSCs in terms of self-renewal, differentiation, and quiescence. (4) Cluster 4 emphasized the crucial role of CSCs in tumor metastasis, invasion, migration as well as their regulation pathways. (5) Cluster 5 focused on CSCs in immunotherapy and tumor microenvironment. This study enhances understanding of research trends and guides future efforts in targeting CSCs for therapeutic interventions, especially in surgical diagnosis and treatment. By illuminating key contributions and emerging themes, it serves as a valuable resource for researchers aiming to advance the field.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.