Evidence map›Paper›PMID 40968693›Full record

ArticleClinical and translational medicine2025

Gene expression differences in differentially methylated sites associated with HIV status and cocaine use.

Eric J Earley, Bryan C Quach, Fang Fang, Laura J Bierut, M-J S Milloy, Kanna Hayashi, Kora DeBeck, Dana B Hancock, Bradley E Aouizerat, Ke Xu and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Clinical and translational medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Eric J EarleyGenOmics and Translational Research Center, RTI International, Durham, North Carolina, USA.
Bryan C QuachGenOmics and Translational Research Center, RTI International, Durham, North Carolina, USA.
Fang FangGenOmics and Translational Research Center, RTI International, Durham, North Carolina, USA.ORCID https://orcid.org/0000-0001-9829-2934
Laura J BierutDepartment of Psychiatry, Washington University School of Medicine, St. Louis, Missouri, USA.
M-J S MilloyBritish Columbia Centre on Substance Use, Vancouver, British Columbia, Canada.
Kanna HayashiBritish Columbia Centre on Substance Use, Vancouver, British Columbia, Canada.
Kora DeBeckBritish Columbia Centre on Substance Use, Vancouver, British Columbia, Canada.
Dana B HancockGenOmics and Translational Research Center, RTI International, Durham, North Carolina, USA.
Bradley E AouizeratBluestone Center for Clinical Research, College of Dentistry, New York University, New York, New York, USA.
Ke XuDepartment of Psychiatry, School of Medicine, Yale University, New Haven, Connecticut, USA.ORCID https://orcid.org/0000-0002-6472-7052
Eric Otto JohnsonGenOmics and Translational Research Center, RTI International, Durham, North Carolina, USA.

Funding

Vancouver Drug Users Study: The Impacts of Evolving Drug Use Patterns on HIV/AIDSU01DA038886 · NIDA · UNIVERSITY OF BRITISH COLUMBIA · PI DEBECK, KORA, HAYASHI, KANNA · 2015 to 2024
$12.1M
Impacts of universal access to HIV/AIDS care among HIV+ injection drug usersU01DA021525 · NIDA · UNIVERSITY OF BRITISH COLUMBIA · PI MILLOY, M-J · 2017 to 2024
$4.3M
Enhancing Discovery of HIV Host Genetics using Drug Abuse and other InteractionsR01DA038632 · NIDA · RESEARCH TRIANGLE INSTITUTE · PI JOHNSON, ERIC OTTO · 2014 to 2018
$3.7M
Gene Network Identification and Integration (GNetii) Approach to Understanding the Biology Underlying HIV and Drug Abuse.R01DA051908 · NIDA · RESEARCH TRIANGLE INSTITUTE · PI JACOBSON, DANIEL A, JOHNSON, ERIC OTTO · 2020 to 2024
$3.4M
Using Omics to Understand the Effects of Drug Abuse on HIV Latent ReservoirR61DA047011 · NIDA · RESEARCH TRIANGLE INSTITUTE · PI AOUIZERAT, BRADLEY E, JOHNSON, ERIC OTTO · 2018 to 2020
$2.4M
Using Omics to Understand the Effects of Drug Abuse on HIV Latent ReservoirR33DA047011 · NIDA · RESEARCH TRIANGLE INSTITUTE · PI AOUIZERAT, BRADLEY E, JOHNSON, ERIC OTTO · 2021 to 2022
$1.4M
NIDA NIH HHS R01DA038632NIDA NIH HHS R01 DA051908NIDA NIH HHS R01DA051908NIDA NIH HHS R33DA047011NIDA NIH HHS R61DA047011NIDA NIH HHS U01 DA021525NIDA NIH HHS U01DA021525NIDA NIH HHS U01 DA038886NIDA NIH HHS U01DA038886
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID40968693
PMCPMC12446875

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.