Evidence map›Paper›PMID 40968691›Full record

ArticleTransfusion2025

Postresuscitation platelet transfusion in major trauma patients.

Andrea Rossetto, Joseph Reynolds, Ella Ykema, Ross Davenport, Elaine Cole, Paul Vulliamy

Abstract read
In one paragraph

Article in Transfusion, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Andrea RossettoCentre for Trauma Sciences, Blizard Institute, Queen Mary University of London, London, UK.ORCID https://orcid.org/0000-0002-9176-8351
Joseph ReynoldsBarts Health National Health Service Trust, London, UK.
Ella YkemaCentre for Trauma Sciences, Blizard Institute, Queen Mary University of London, London, UK.
Ross DavenportCentre for Trauma Sciences, Blizard Institute, Queen Mary University of London, London, UK.
Elaine ColeCentre for Trauma Sciences, Blizard Institute, Queen Mary University of London, London, UK.
Paul VulliamyCentre for Trauma Sciences, Blizard Institute, Queen Mary University of London, London, UK.

Funding

TEM International GmbH (Munich, Germany)Wellcome TrustWellcome Trust (Early Career Award) 309168/Z/24/Z
6 · The paper itself

Abstract

backgroundPlatelet transfusions (PLT-t) are a cornerstone of contemporary trauma resuscitation, but little is known about their use in the postresuscitation period. Our aims were to describe the utilization of PLT-t after resuscitation and examine their impact on platelet count and clinical outcomes. STUDY DESIGN AND

methodsAdult trauma patients admitted to critical care at a single major trauma center were included. We compared patients who received PLT-t postresuscitation (>24 h after injury) with those who did not and examined platelet increments before and after each individual PLT-t episode. Logistic regressions were constructed to examine the association between postresuscitation PLT-t and clinical outcomes.

resultsThis study included 803 injured patients, of whom 109 (14%) received at least one PLT-t after resuscitation. Overall, 30% (221/725) of all platelet units administered to the cohort were given in the postresuscitation phase, most in the first week of admission and to patients with moderate-severe thrombocytopenia. The median platelet count increment following transfusion was 19 × 10

conclusionPostresuscitation PLT-t is frequently administered in trauma patients. The impact on platelet counts is variable, likely attributable to differences in timing and pretransfusion platelet count. After adjusting for relevant confounders, postresuscitation PLT-t was associated with reduced mortality in this cohort.

Indexed as

Platelet TransfusionResuscitationWounds and InjuriesAdultAgedFemaleHumansMaleMiddle AgedPlatelet CountRetrospective StudiesThrombocytopeniaTrauma Centerscritical caremortalityplatelet transfusionthrombocytopeniatrauma

Identifiers

PMID40968691
PMCPMC12618904

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.