Evidence map›Paper›PMID 40968322›Full record

ReviewJournal of molecular evolution2025

Fascination with RNA Editing: In the Lights of Evolution and Biology.

Ziyi Wang, Yuange Duan

Abstract readReview
PubMed Publisher
In one paragraph

Review in Journal of molecular evolution, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Ziyi WangDepartment of Entomology, State Key Laboratory of Agricultural and Forestry Biosecurity, MOA Key Lab of Pest Monitoring and Green Management, College of Plant Protection, China Agricultural University, Beijing, 100193, China.
Yuange DuanDepartment of Entomology, State Key Laboratory of Agricultural and Forestry Biosecurity, MOA Key Lab of Pest Monitoring and Green Management, College of Plant Protection, China Agricultural University, Beijing, 100193, China. duanyuange@cau.edu.cn.ORCID 0000-0003-2311-9859

Funding

Natural Science Foundation of Beijing Municipality 6252012Young Elite Scientist Sponsorship Program by BAST BYESS2023160Young Elite Scientist Sponsorship Program by CAST 2023QNRC001
6 · The paper itself

Abstract

Adenosine-to-inosine RNA editing is a widespread RNA modification that recodes genetic information and expands proteomic diversity. Exploring its evolutionary and adaptive roles requires multi-dimensional analysis, from sequence conservation to functional impact. In this article, we highlight RNA editing as a fascinating bridge between molecular biology and evolutionary theory-two domains used to be treated separately. Remarkably, RNA editing embodies both diversity (as a consequence of mutation, drift, and selection) and conservation (common ancestor), the two foundational principles of Darwin's theory and modern evolutionary research. While some evolutionary studies emphasize what has changed over time, RNA editing additionally draws attention to conserved signatures that persist across lineages, offering a more integrative perspective on how species evolve while remaining connected through shared molecular ancestry.

Indexed as

Biological EvolutionEvolution, MolecularRNA EditingAdenosineAnimalsHumansInosineMutationAdenosineInosineBiologyCommon ancestorEvolutionMutation and selectionRNA editing

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.