Evidence map›Paper›PMID 40968301›Full record

ArticleDigestive diseases and sciences2026

Prevalence and Clinical Features of Incidental Inflammatory Bowel Disease Identified During Screening and Surveillance Colonoscopy.

Sergio Bronze, Shabari Shenoy, Manasi Agrawal, Alexandros D Polydorides, Jean-Frédéric Colombel, Iago Rodríguez-Lago, Ryan C Ungaro

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Article in Digestive diseases and sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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0cells of the map it votes in
1citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Sergio BronzeGastroenterology and Hepatology Department, Unidade Local de Saúde de Santa Maria, Lisbon, Portugal.
Shabari ShenoyDepartment of Hospital Medicine, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Manasi AgrawalDivision of Gastroenterology, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Alexandros D PolydoridesDepartment of Pathology, Molecular, and Cell-Based Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Jean-Frédéric ColombelDivision of Gastroenterology, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Iago Rodríguez-LagoGastroenterology Department, Hospital Universitario de Galdakao, Biobizkaia Health Research Institute, Galdakao, Spain.
Ryan C UngaroDivision of Gastroenterology, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA. ryan.ungaro@mssm.edu.

Funding

Eusko Jaurlaritza 2020111061NIDDK NIH HHS K23DK129762-03
6 · The paper itself

Abstract

backgroundInflammatory bowel disease (IBD) can be detected in the absence of clinical symptoms.

aimsTo determine the prevalence of incidental IBD in patients undergoing screening colonoscopy and to explore its clinical features and long-term outcomes.

methodsWe conducted a retrospective cohort study that included all asymptomatic adults who underwent colonoscopy for colorectal cancer screening or polyp surveillance between 2009 and 2023 in a large health system. Incidental IBD was defined as endoscopic and histologic findings consistent with the disease in the absence of symptoms. Clinical characteristics and outcomes were collected.

resultsAmong 40,573 patients who underwent colonoscopy, 60 were diagnosed with incidental IBD: 40 with Crohn's disease (CD), 10 with ulcerative colitis (UC), and 10 with IBD-unclassified (IBD-U). Mean age at diagnosis was 54.6 years for CD, 52.8 years for UC, and 55.7 years for IBD-U, with an overall female predominance (53%). Most CD patients had ileal involvement (98%) and inflammatory behavior (98%), and 60% of UC patients had extensive disease. After a mean follow-up period of 27.9 ± 34.7 months, 10 (16.7%) patients developed symptoms, and 5 (8.3%) initiated therapy, mostly after symptom onset. No hospitalizations or surgeries were reported.

conclusionThe prevalence of incidental IBD detected during colorectal cancer screening is low (0.15%), with 20% of CD and 20% of UC cases progressing to symptomatic disease. Incidental IBD has a mild disease course with a low likelihood of progression to complications.

Indexed as

Colorectal cancer screeningCrohn’s diseaseFITIncidental IBDInflammatory bowel diseaseUlcerative colitis

Identifiers

PMID40968301

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