Evidence map›Paper›PMID 40968244›Full record

ArticleJournal of molecular histology2025

LOXL1-AS1 suppresses ferroptosis in cervical cancer through m6A-dependent regulation of TFRC.

Hongyou Wang, Jianbo Zhou, Jianfeng Zhang, Wenlei Yao, Haiyang Li, Kangjie Xu, Hui Cheng

Abstract read
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In one paragraph

Article in Journal of molecular histology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Hongyou Wang *Department of Obstetrics and Gynecology, Binhai County People's Hospital, Yancheng, 224500, Jiangsu, China.
Jianbo Zhou *Department of Obstetrics and Gynecology, Binhai County People's Hospital, Yancheng, 224500, Jiangsu, China.
Jianfeng ZhangDepartment of Chinese and Western Medicine Integrative Gynecology, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, 200011, China.
Wenlei YaoDepartment of Obstetrics and Gynecology, Binhai County People's Hospital, Yancheng, 224500, Jiangsu, China.
Haiyang LiDepartment of Oncology, Binhai County People's Hospital, Yancheng, 224500, Jiangsu, China.
Kangjie XuDepartment of Central Laboratory, Binhai County People's Hospital, Yancheng, 224500, Jiangsu, China.
Hui ChengDepartment of General Surgery, Binhai County People's Hospital, Yancheng, 224500, Jiangsu, China. chenghui_edu@outlook.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Transferrin receptor (TFRC) is essential for iron uptake and may regulate ferroptosis, a form of iron-dependent cell death implicated in cervical cancer (CC). Bioinformatic analyses (GEPIA, UALCAN, SRAMP, starBase) were combined with in vitro and in vivo experiments. CC cell lines were transfected with shRNAs or overexpression plasmids targeting TFRC and LOXL1-AS1. Proliferation was assessed by colony formation, EdU staining, and Ki-67 immunostaining. Ferroptosis was evaluated by measuring malondialdehyde (MDA), lipid ROS, Fe

Indexed as

FerroptosisReceptors, TransferrinRNA, Long NoncodingUterine Cervical NeoplasmsAnimalsCell Line, TumorCell ProliferationFemaleGene Expression Regulation, NeoplasticHumansMiceMice, NudeReceptors, TransferrinRNA, Long NoncodingCervical cancerFerroptosisIGF2BP2LOXL1-AS1N6-methyladenosineTFRC

Identifiers

PMID40968244

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.