Evidence map›Paper›PMID 40967975›Full record

ArticleThe Journal of surgical research2025

Cost-Effectiveness and Cost Only Studies for Inflammatory Bowel Disease Surgery: A Scoping Review.

Ira L Leeds, Arabella Dill-Macky, Christopher Prien, Hengjian Li, Eddy Lincango, Benjamin C Cohen, Stefan D Holubar

Abstract readScoping Review
In one paragraph

Article in The Journal of surgical research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ira L LeedsDivision of Colon & Rectal Surgery, Department of Surgery, Yale School of Medicine, New Haven, Connecticut. Electronic address: ira.leeds@yale.edu.
Arabella Dill-MackyDivision of Colon & Rectal Surgery, Department of Surgery, Yale School of Medicine, New Haven, Connecticut.
Christopher PrienCleveland Clinic Foundation, Department of Colorectal Surgery, Cleveland, Ohio.
Hengjian LiDivision of Colon & Rectal Surgery, Department of Surgery, Yale School of Medicine, New Haven, Connecticut.
Eddy LincangoCleveland Clinic Foundation, Department of Colorectal Surgery, Cleveland, Ohio.
Benjamin C CohenCleveland Clinic Foundation, Department of Gastroenterology & Hepatology, Cleveland, Ohio.
Stefan D HolubarCleveland Clinic Foundation, Department of Colorectal Surgery, Cleveland, Ohio.

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
NCATS NIH HHS UL1 TR001863
6 · The paper itself

Abstract

introductionStudies examining the cost-effectiveness of surgical procedures and surgery-related interventions in patients with inflammatory bowel disease (IBD) remain limited. This dearth of studies hampers decision-makers' assessment of surgery-related interventions for patients with IBD. This study aimed to conduct a scoping review of the available literature for cost-effectiveness analyses of IBD-related surgery.

methodsWe performed a comprehensive search in common publication registries. Preplanned controlled vocabulary related to IBD and its subtypes, surgery, and cost measures were used. We defined the study selection criteria to include all IBD-related surgical interventions that also reported a measure of costs of care. Studies for medical versus surgical interventions for refractory IBD were excluded. All search findings were screened by two reviewers using titles, abstracts, and ultimately full-length manuscripts. Fully screened studies were then extracted to facilitate a qualitative synthesis of results.

resultsWe identified seven formal cost-effectiveness studies and 55 cost only studies. Cost-effectiveness studies assessed intraoperative (42.9%) and postoperative interventions (57.1%), mostly in patients with Crohn's disease (71.4%). Topics included surgical approaches (42.8%), venous thromboembolism prophylaxis (28.6%), and surveillance for postoperative recurrence (28.6%). Of the cost only studies, most focused on intraoperative interventions (81.8%), particularly in ulcerative colitis patients (45.5%). Predefined areas with no reported interventions included enhanced recovery interventions, robotic surgery, timing to surgery, perianal disease, pediatric disease, and genetic testing.

conclusionsThis scoping review found minimal cost-effectiveness literature to inform IBD-related surgical care. There were many more cost only studies than cost-effectiveness studies related to these clinical topics. This asymmetry highlights immediately available opportunities to broaden the use of cost-effectiveness analyses for IBD-related surgical interventions.

Indexed as

Crohn DiseaseDigestive System Surgical ProceduresInflammatory Bowel DiseasesCost-Benefit AnalysisHumansClinical trialsCostsInflammatory bowel diseaseSocio-economical end pointsSurgery

Identifiers

PMID40967975
PMCPMC12453598

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.