Evidence map›Paper›PMID 40967803›Full record

ArticleInternal medicine (Tokyo, Japan)2026

Prosthetic Joint Infection Caused by Streptococcus pneumoniae Serotype 15F: A Rare Manifestation of an Emerging Non-vaccine Serotype.

Masaji Saijo, Shadia Constantine, Toshiaki Wakai, Akihiro Sakuma, Sachiko Ando, Satoshi Takayanagi

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Masaji SaijoPrimary Center, Sapporo Tokushukai Hospital, Japan.
Shadia ConstantinePrimary Center, Sapporo Tokushukai Hospital, Japan.
Toshiaki WakaiDepartment of Family Medicine, University of Michigan, USA.
Akihiro SakumaDepartment of Radiology, Sapporo Tokushukai Hospital, Japan.
Sachiko AndoDepartment of Emergency Medicine, Sapporo Tokushukai Hospital, Japan.
Satoshi TakayanagiDepartment of Orthopedic Surgery, Shonan Kamakura Joint Reconstruction Center, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Prosthetic joint infection (PJI) caused by Streptococcus pneumoniae is rare, particularly in the absence of bacteremia. This case report describes a 69-year-old Japanese woman with a history of follicular lymphoma and bilateral total hip arthroplasty who developed a right periprosthetic abscess caused by S. pneumoniae. This was an unusual presentation as the patient lacked typical respiratory or neurological symptoms or bacteremia. The causative strain was identified as serotype 15F, a non-vaccine serotype (NVT) not covered by current pneumococcal vaccines. This case highlights serotype replacement, where NVT infections emerge because of widespread vaccination, potentially presenting atypically and exhibiting antibiotic resistance.

Indexed as

Pneumococcal InfectionsProsthesis-Related InfectionsStreptococcus pneumoniaeAgedAnti-Bacterial AgentsArthroplasty, Replacement, HipFemaleHumansPneumococcal VaccinesSerogroupAnti-Bacterial AgentsPneumococcal Vaccinesnon-vaccine serotypes (NVTs)pneumococcal conjugate vaccine (PCV)prosthetic joint infection (PJI)serotype 15Fserotype replacementStreptococcus pneumoniae

Identifiers

PMID40967803
PMCPMC13175671

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.