ArticleInternal medicine (Tokyo, Japan)2026
Severe Bilateral Optic Neuritis and a Tumefactive Demyelinating Lesion in Pregnancy.
Article in Internal medicine (Tokyo, Japan), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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1 citing paper in PubMed.
- Optic Neuritis in the Puerperium Mimicking Severe Preeclampsia: A Neurological Differential Diagnosis in the Obstetric Emergency Setting.Clinical case reports · 2026Article
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4 authors.
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Abstract
A 40-year-old pregnant woman developed severe bilateral optic neuritis and a tumefactive demyelinating lesion (TDL) in the first trimester. Although her bilateral optic neuritis improved with intravenous methylprednisolone, plasma exchange, and intravenous immunoglobulin, the TDL lesion expanded, and the accompanying symptoms worsened. Following a shared decision-making process, the patient received ofatumumab after repeated steroid pulse therapy. Subsequently, the lesion enlargement stopped and there was no exacerbation of the symptoms. This case demonstrates the challenges and management of a rare condition involving co-occurrence of severe bilateral optic neuritis and a TDL during pregnancy.
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