ArticleThe Journal of veterinary medical science2025
Epidemiological analysis and detection of a 27a-like porcine parvovirus strain with pathogenicity in pregnant sows in Japan.
Article in The Journal of veterinary medical science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Porcine parvovirus (PPV) is a major cause of reproductive failure in pigs. This study reports the first detection of a PPV 27a-like strain in Japan. A total of 387 samples from 113 cases (2015-2024) were analyzed, revealing 35 PPV-positive cases. Phylogenetic analysis identified the NG2794-2-3/2019 strain as a 27a-like variant. Experimental infection in pregnant sows resulted in fetal death and mummification, confirming pathogenicity. The strain exhibited prolonged viremia, indicating a high transmission risk. Owing to antigenic differences from vaccine strains, conventional PPV vaccines may be ineffective. This study highlights the urgent need for enhanced vaccines to control PPV-related reproductive disorders in Japan.
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