Evidence map›Paper›PMID 40967183›Full record

ArticleCell systems2025

The Adaptive Immune Receptor Repertoire Knowledge Commons: An invitation to the community.

Lindsay G Cowell, Scott Christley, Felix Breden, Kevin A Burns, Brian D Corrie, William D Lees, James A Overton, Bjoern Peters, Eve Richardson, Krishna M Roskin and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cell systems, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Revised Adaptive Immune Receptor Data in the Immune Epitope Database.bioRxiv : the preprint server for biology · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Lindsay G CowellDepartment of Health Data Sciences and Biostatistics, Peter O'Donnell Jr. School of Public Health, UT Southwestern Medical Center, Dallas, TX, USA; Department of Immunology, School of Biomedical Sciences, UT Southwestern Medical Center, Dallas, TX, USA. Electronic address: lindsay.cowell@utsouthwestern.edu.
Scott ChristleyDepartment of Health Data Sciences and Biostatistics, Peter O'Donnell Jr. School of Public Health, UT Southwestern Medical Center, Dallas, TX, USA.
Felix BredenDepartment of Biological Sciences, Faculty of Science, Simon Fraser University, Burnaby, BC, Canada.
Kevin A BurnsDivision of Biomedical Informatics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA; Department of Pediatrics, College of Medicine, University of Cincinnati, Cincinnati, OH, USA.
Brian D CorrieDepartment of Biological Sciences, Faculty of Science, Simon Fraser University, Burnaby, BC, Canada.
William D LeesClareo Biosciences Inc., Louisville, KY, USA.
James A OvertonKnocean Inc., Toronto, ON, Canada.
Bjoern PetersCenter for Vaccine Innovation, La Jolla Institute for Immunology, La Jolla, CA, USA.
Eve RichardsonCenter for Vaccine Innovation, La Jolla Institute for Immunology, La Jolla, CA, USA.
Krishna M RoskinDivision of Biomedical Informatics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA; Department of Pediatrics, College of Medicine, University of Cincinnati, Cincinnati, OH, USA.
Lonneke SchefferCenter for Vaccine Innovation, La Jolla Institute for Immunology, La Jolla, CA, USA.
Randi VitaCenter for Vaccine Innovation, La Jolla Institute for Immunology, La Jolla, CA, USA.
Corey T WatsonDepartment of Biochemistry and Molecular Genetics, University of Louisville School of Medicine, Louisville, KY 40202, USA.
Gur YaariDepartment of Pathology, Yale School of Medicine, New Haven, CT, USA.

Funding

i-AKC: Integrated AIRR Knowledge CommonsU24AI177622 · NIAID · UT SOUTHWESTERN MEDICAL CENTER · PI LINDSAY G. COWELL · 2023 to 2026
$4.0M
NIAID NIH HHS U24 AI177622
6 · The paper itself

Abstract

Sequencing data elucidating adaptive immune receptor (AIR) repertoires, genomic loci encoding AIR genes, and AIR antigens are hosted in siloed repositories, limiting integrative analyses. We are in the process of creating the AIR Repertoire Knowledge Commons (AKC) by merging data from community-backed repositories and applying knowledge-generation algorithms to integrate and enrich data and metadata.

Indexed as

Adaptive ImmunityReceptors, ImmunologicAlgorithmsAnimalsComputational BiologyHumansReceptors, Immunologic

Identifiers

PMID40967183
PMCPMC13189698

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.