Evidence map›Paper›PMID 40966659›Full record

ArticleDento maxillo facial radiology2026

Carotid artery calcifications on panoramic radiographs are associated with vascular disease severity on carotid ultrasound.

Astrid Karlsson, Nils Gustafsson, Per Wester, Liene Zamure-Damberga, Eva Levring Jäghagen

Abstract read
In one paragraph

Article in Dento maxillo facial radiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Astrid KarlssonOral and Maxillofacial Radiology, Department of Odontology, Umeå University, SE-90187 Umeå, Sweden.ORCID 0009-0005-4772-9928
Nils GustafssonOral and Maxillofacial Radiology, Department of Odontology, Umeå University, SE-90187 Umeå, Sweden.ORCID 0000-0003-1120-8993
Per WesterDepartment of Public Health and Clinical Medicine, Umeå University, SE-90187 Umeå, Sweden.ORCID 0000-0003-0394-5096
Liene Zamure-DambergaOral and Maxillofacial Radiology, Department of Odontology, Umeå University, SE-90187 Umeå, Sweden.ORCID 0000-0001-8875-973X
Eva Levring JäghagenOral and Maxillofacial Radiology, Department of Odontology, Umeå University, SE-90187 Umeå, Sweden.ORCID 0000-0001-8807-3500

Funding

Carl Bennet LtdCO Henriksons FoundationHeart and Lung Foundation 371130519Heart and Lung Foundation 371130520Heart and Lung Foundation HLF 20150369King Gustaf V and Queen Victoria's FoundationSwedish Research Council Dnr 521-2013-2708, 2017-02891TUAVästerbotten County Council 298001Västerbotten County Council 643391Västerbotten County Council 7004491Västerbotten County Council 7004571
6 · The paper itself

Abstract

objectivesThe aim of this study was to investigate whether any feature of carotid artery calcification (CAC) detected on panoramic radiographs (PRs) is associated with more severe signs of cardiovascular disease (CVD), as assessed by carotid ultrasound (CUS) including multi-view assessment of carotid intima media thickness (cIMT).

methodsThe present investigation was a retrospective sub-study of the randomized controlled trial visualization of asymptomatic atherosclerotic disease for optimum cardiovascular prevention (VIPVIZA), which included 60-, 50-, and 40-year-old inhabitants of Västerbotten County, each of whom underwent CUS. The present sub-study included 135 participants who had undergone PR for odontological indications within 18 months before or after CUS examination. Findings of CAC on PR were compared with CUS findings of cIMT and carotid plaque. CAC features were categorized into 4 types: single, scattered, vessel width-defining, or vessel-outlining.

resultsCompared to participants without CAC on PR, those with any CAC type on PR exhibited significantly more carotid plaque (80.9% vs 43.2%, P < .001) and a higher average cIMT score (0.83 vs 0.77 mm, P = .013) on CUS. The vessel-outlining CAC group exhibited the most pronounced cIMT and carotid plaque occurrence (P = .011).

conclusionsAll CAC types detected on PR were associated with CVD on CUS, and vessel-outlining CAC indicated more severe CVD. By detecting CAC on PR, especially vessel-outlining CACs, dentists could contribute to the early identification of patients with asymptomatic CVD, and recommend that these patients seek medical attention for preventive treatment. ADVANCES IN KNOWLEDGE: All types of CAC detected on PR-particularly the vessel-outlining type-are associated with carotid ultrasound findings, including carotid intima media thickness, indicating CVD and increased risk of stroke and myocardial infarction. Thus, dentists can identify patients at increased risk of cardiovascular events by detecting CAC  on PR, with higher diagnostic reliability in cases with vessel-outlining calcification.

Indexed as

Carotid Artery DiseasesRadiography, PanoramicVascular CalcificationAdultCarotid Intima-Media ThicknessFemaleHumansMaleMiddle AgedRetrospective StudiesSeverity of Illness IndexUltrasonographyUltrasonography, Carotid Arteriesaccuracycarotid arteriespanoramicradiographyultrasonography

Identifiers

PMID40966659
PMCPMC12796716

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.