ArticlePLOS digital health2025
Predicting patient enrollment in a telephone-based principal care management service using topic modeling.
Article in PLOS digital health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Authors and funding
6 authors.
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Abstract
Diabetic Retinopathy (DR) is a complication related to diabetes that can lead to vision impairment. To assist DR patients, a care management company provides a telephone-based principal care management (PCM) service, which includes care coaching and other services to reduce barriers to care for patients with DR. Despite its benefits, enrollment in the program is suboptimal. This study developed predictive models using call transcripts to investigate factors associated with patient enrollment in the PCM service. We analyzed transcripts of calls made during the enrollment process (prior to enrollment) and feature-engineered the call metadata (i.e., transcript length, number of calls, time between calls, customer and agent sentiment). In addition, we extracted topics discussed in the transcripts using Structural Topic Modeling (STM) and converted them into vector representations. Utilizing call metadata alongside topics, we developed three classification models (call metadata, topic-based, and topic+metadata) to predict patient enrollment, with the latter demonstrating superior performance. The topic+metadata classification model outperformed the other two models in distinguishing between patient enrollment and non-enrollment, with AUC values ranging from 0.81 to 0.99 across models using 3 to 15-topics. The findings suggest that proactively offering to schedule an appointment after the program benefits explanation leads to a higher odds of enrollment. When the scheduling portion of the conversation is not considered, agents should cover all parts of the script over multiple calls. Additionally, agents who explain the program and maintain longer intervals between calls have higher odds of patient enrollment, suggesting that there is value in allowing patients adequate time to reflect between calls. These findings offer valuable insights for agents to evaluate their strategies in patient enrollment. As the first point of contact, enrollment agents play a crucial role in determining whether patients can benefit from care coordination and management programs.
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Registered trials
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