Evidence map›Paper›PMID 40966291›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2025

A model for boundary-driven tissue morphogenesis.

Daniel S Alber, Shiheng Zhao, Alexandre O Jacinto, Eric F Wieschaus, Stanislav Y Shvartsman, Pierre A Haas

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. The role of geometry in morphogenesis.Development (Cambridge, England) · 2026
    Review
  2. Article
  3. Article
  4. A model for boundary-driven tissue morphogenesis.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  5. Dynamical systems of fate and form in development.Seminars in cell & developmental biology · 2025
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Daniel S Alber *Department of Chemical and Biological Engineering, Princeton University, Princeton, NJ 08540.ORCID 0000-0003-3057-995X
Shiheng Zhao *Max Planck Institute for the Physics of Complex Systems, Dresden 01187, Germany.ORCID 0009-0003-0024-5999
Alexandre O JacintoCenter for Computational Biology, Flatiron Institute, Simons Foundation, New York, NY 10010.
Eric F WieschausThe Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, NJ 08540.
Stanislav Y ShvartsmanThe Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, NJ 08540.ORCID 0000-0002-9152-9334
Pierre A HaasMax Planck Institute for the Physics of Complex Systems, Dresden 01187, Germany.ORCID 0000-0002-6663-0393

Funding

Collective dynamics in cell clustersR01GM134204 · NIGMS · PRINCETON UNIVERSITY · PI Stanislav Y. Shvartsman · 2019 to 2026
$2.6M
HHS | NIH | National Institute of General Medical Sciences (NIGMS) R01GM134204National Science Foundation (NSF) DGE-2039656NIGMS NIH HHS R01 GM134204
6 · The paper itself

Abstract

Tissue deformations during morphogenesis can be active, driven by internal processes, or passive, resulting from stresses applied at their boundaries. Here, we introduce the

Indexed as

DrosophilaDrosophila melanogasterModels, BiologicalMorphogenesisAnimalsBiomechanical PhenomenaEmbryo, NonmammalianDrosophila developmentmechanical bifurcationmorphogenesistissue mechanics

Identifiers

PMID40966291
PMCPMC12478147

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.