Evidence map›Paper›PMID 40966257›Full record

ArticlePloS one2025

The role of educational attainment and quality in U.S. regional variation in prevalence of dementia and CIND.

Jennifer A Ailshire, Mateo P Farina, Heide Jackson, Katrina M Walsemann

Abstract read
In one paragraph

Article in PloS one, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jennifer A AilshireLeonard Davis School of Gerontology, University of Southern California, Los Angeles, California, United States of America.ORCID 0000-0002-4476-9458
Mateo P FarinaDepartment of Human Development and Family Sciences, University of Texas at Austin, Austin, Texas, United States of America.
Heide JacksonPopulation Research Center, University of Maryland, College Park, Maryland, United States of America.ORCID 0000-0002-0228-3855
Katrina M WalsemannSchool of Public Policy, University of Maryland, College Park, Maryland, United States of America.

Funding

HRS Yrs29-34: Y33 SSA CoFundingU01AG009740 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Jessica Faul, KENNETH M LANGA · 1990 to 2026
$555.8M
State and Local Educational Contexts of Older U.S. Adults and Their Association with Cognitive Impairment and DementiaR01AG067536 · NIA · UNIV OF MARYLAND, COLLEGE PARK · PI WALSEMANN, KATRINA · 2020 to 2024
$2.0M
NIA NIH HHS R01 AG067536NIA NIH HHS U01 AG009740
6 · The paper itself

Abstract

There are striking disparities in dementia prevalence across regions of the U.S. Education is one of the most important risk factors for dementia. Level and quality of education varied geographically for older cohorts of U.S. adults, potentially contributing to regional differences in dementia prevalence. This study links historical state education quality data to respondents ages 65 and older in the Health and Retirement Study to determine the extent to which geographic disparities in dementia and cognitive impairment with no dementia (CIND) can be attributed to state-level measures of education quality. Older adults educated in states with better resourced education systems had lower prevalence of dementia (Relative risk ratio (RRR): 0.81; CI: 0.75, 0.87) and CIND (RRR: 0.89; CI: 0.84, 0.93), while those educated in states where more school funding came from state rather than local sources had higher prevalence of dementia (RRR: 1.12; CI: 1.01, 1.23) and CIND (RRR: 1.10; CI: 1.03, 1.16). Educational attainment does not explain the higher prevalence of dementia or CIND in the US South, but state-level education quality fully accounted for higher prevalence of dementia and CIND in the South. Finally, state-level education quality indicators were more strongly associated with dementia and CIND among those with less education These findings suggest education does in fact explain regional disparities in dementia and cognitive impairment, particularly between the South and other regions, but that it is the educational environment that matters more for geographic differences than educational attainment in these cohorts.

Indexed as

Cognitive DysfunctionDementiaEducational StatusAgedAged, 80 and overFemaleHumansMalePrevalenceRisk FactorsUnited States

Identifiers

PMID40966257
PMCPMC12445459

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.